Exploring of novel 4-hydroxy-2H-benzo [e][1, 2] thiazine-3-carbohydrazide 1, 1-dioxide derivative as a dual inhibitor of α-glucosidase and α-amylase: Molecular …
Diabetes mellitus (DM) is a metabolic disorder that leads to hyperglycemia due to improper
insulin secretion. The study aims to investigate the anti-diabetic potential of benzothiazine …
insulin secretion. The study aims to investigate the anti-diabetic potential of benzothiazine …
[HTML][HTML] Integrating Pharmacological and Computational Approaches for the Phytochemical Analysis of Syzygium cumini and Its Anti-Diabetic Potential
F Rashid, A Javaid, UA Ashfaq, M Sufyan… - Molecules, 2022 - mdpi.com
Diabetes mellitus (DM) is a metabolic disease caused by improper insulin secretion leading
to hyperglycemia. Syzygium cumini has excellent therapeutic properties due to its high …
to hyperglycemia. Syzygium cumini has excellent therapeutic properties due to its high …
[HTML][HTML] Identification of Cyclic Sulfonamides with an N-Arylacetamide Group as α-Glucosidase and α-Amylase Inhibitors: Biological Evaluation and Molecular …
Diabetes mellitus (DM), a complicated metabolic disorder, is due to insensitivity to insulin
function or reduction in insulin secretion, which results in postprandial hyperglycemia. α …
function or reduction in insulin secretion, which results in postprandial hyperglycemia. α …
[HTML][HTML] Synthesis and α-Glucosidase Inhibition Activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2H-benzo[e][1,2]thiazin-2-yl]-N-arylacetamides: An …
Diabetes mellitus (DM) is a chronic disorder and has affected a large number of people
worldwide. Insufficient insulin production causes an increase in blood glucose level that …
worldwide. Insufficient insulin production causes an increase in blood glucose level that …
Synthesis, molecular docking and anti-diabetic studies of novel benzimidazole-pyrazoline hybrid molecules
: Pyrazoline and benzimidazoles derivatives have been widely studied due to their potential
applications in the medicinal field. In this research project, we have hybridized these two …
applications in the medicinal field. In this research project, we have hybridized these two …
Synthesis, single crystal X-ray, spectroscopic and computational (DFT) studies 2, 1-benzothiazine based hydrazone derivatives
Benzothiazine-4 (3H)-one 2, 2-dioxide was synthesized through a multistep procedure
starting with methyl anthranilate. It was reacted with hydrazine monohydrate to form …
starting with methyl anthranilate. It was reacted with hydrazine monohydrate to form …
[HTML][HTML] The antihyperglycemic potential of pyrazolobenzothiazine 1, 1-dioxide novel derivative in mice using integrated molecular pharmacological approach
Diabetes Mellitus is a metabolic disease characterized by elevated blood sugar levels
caused by inadequate insulin production, which subsequently leads to hyperglycemia. This …
caused by inadequate insulin production, which subsequently leads to hyperglycemia. This …
Synthesis and α-glucosidase inhibition studies of norfloxacinacetanilide hybrids.
Abstract α-Glucosidase inhibitors occupy a prominent position among the various treatments
of type-2 diabetes mellitus (DM2). In this study, a series of new norfloxacin-acetanilide …
of type-2 diabetes mellitus (DM2). In this study, a series of new norfloxacin-acetanilide …
[HTML][HTML] Exploration of the Interactions between Maltase–Glucoamylase and Its Potential Peptide Inhibitors by Molecular Dynamics Simulation
S Guan, X Han, Z Li, X Xu, Y Cui, Z Chen, S Zhang… - Catalysts, 2022 - mdpi.com
Diabetes mellitus, a chronic metabolic disorder, represents a serious threat to human health.
The gut enzyme maltase–glucoamylase (MGAM) has attracted considerable attention as a …
The gut enzyme maltase–glucoamylase (MGAM) has attracted considerable attention as a …
[PDF][PDF] Mahmood-ur-Rahman
F Rashid, A Javaid - Ashfaq, UA - academia.edu
Diabetes mellitus (DM) is a metabolic disease caused by improper insulin secretion leading
to hyperglycemia. Syzygium cumini has excellent therapeutic properties due to its high …
to hyperglycemia. Syzygium cumini has excellent therapeutic properties due to its high …