Chondroitin sulfate (CS) is the most abundant and widely distributed glycosaminoglycan
(GAG) in the human body. As a component of proteoglycans (PGs) it has numerous roles in …

Background Cancer metastasis is the main obstacle to increasing the lifespan of cancer
patients. Epithelial-to-mesenchymal transition (EMT) plays a significant role in oncogenic …

Growing evidence points to a critical involvement of the extracellular matrix (ECM) in the
pathophysiology of schizophrenia (SZ). Decreases of perineuronal nets (PNNs) and altered …

Using expression cloning to screen a human fetal kidney cDNA library for regulator (s) of pro-
matrix metalloproteinase (MMP)-2 processing mediated by membrane-type (MT) 1 MMP, we …

Prostate cancer is the most diagnosed noncutaneous cancer and ranks as the second
leading cause of cancer-related deaths in American males. Metastasis is the primary cause …

Chondroitin sulphate (CS) glycosaminoglycan chains on cell and extracellular matrix
proteoglycans (PGs) can no longer be regarded as merely hydrodynamic space fillers …

Testican family proteins are putative extracellular heparan/chondroitin sulfate proteoglycans
of unknown function. We identified recently N-Tes, which is a product of testican 3 splicing …

Tenascin-C is an extracellular matrix protein over-expressed in a large variety of cancers. In
the present study, we aimed at identifying new interactors of tenascin-C by purifying …

For females, menarche is a most significant physiological event. Age at menarche (AAM) is a
trait with high genetic determination and is associated with major complex diseases in …

Central and peripheral nervous system (CNS/PNS) proteoglycans (PGs) have diverse
functional roles, this study examined how these control cellular behavior and tissue function …