MOF materials as therapeutic agents, drug carriers, imaging agents and biosensors in cancer biomedicine: Recent advances and perspectives
A Bieniek, AP Terzyk, M Wiśniewski, K Roszek… - Progress in Materials …, 2021 - Elsevier
We summarize recent advances in application of MOFs as therapeutic agents, drug carriers,
imaging agents and biosensors in cancer biomedicine. A holistic perspective is adopted to …
imaging agents and biosensors in cancer biomedicine. A holistic perspective is adopted to …
Targeting telomeres and telomerase
A De Cian, L Lacroix, C Douarre, N Temime-Smaali… - Biochimie, 2008 - Elsevier
Telomeres and telomerase represent, at least in theory, an extremely attractive target for
cancer therapy. The objective of this review is to present the latest view on the mechanism …
cancer therapy. The objective of this review is to present the latest view on the mechanism …
New drugs are not enough-drug repositioning in oncology: An update
RG Armando, DLM Gomez… - … Journal of Oncology, 2020 - spandidos-publications.com
Drug repositioning refers to the concept of discovering novel clinical benefits of drugs that
are already known for use treating other diseases. The advantages of this are that several …
are already known for use treating other diseases. The advantages of this are that several …
[HTML][HTML] The versatile emodin: A natural easily acquired anthraquinone possesses promising anticancer properties against a variety of cancers
Q Zhang, WW Chen, X Sun, D Qian… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Cancers are generally recognized as the leading cause of death and a predominant barrier
to prolonging life expectancy in both developed and developing countries. Emodin is a …
to prolonging life expectancy in both developed and developing countries. Emodin is a …
New organochalcogen multitarget drug: Synthesis and antioxidant and antitumoral activities of chalcogenozidovudine derivatives
In this article we present the synthesis, characterization, and in vitro biological and
biochemical activities of new chalcogenozidovudine derivatives as antioxidant (inhibition of …
biochemical activities of new chalcogenozidovudine derivatives as antioxidant (inhibition of …
Repurposing of antimicrobial agents for cancer therapy: what do we know?
C Pfab, L Schnobrich, S Eldnasoury, A Gessner… - Cancers, 2021 - mdpi.com
Simple Summary Despite the leaps and bounds in the prevention and treatment of cancer, it
remains the second leading cause of death worldwide. A significant hurdle during cancer …
remains the second leading cause of death worldwide. A significant hurdle during cancer …
Mechanisms of zidovudine-induced mitochondrial toxicity and myopathy
ER Scruggs, AJ Dirks Naylor - Pharmacology, 2008 - karger.com
Abstract Zidovudine (3-azido-3′-deoxythymidine), also referred to as azidothymidine (AZT),
has become an integral component in highly active antiretroviral therapy, and has also been …
has become an integral component in highly active antiretroviral therapy, and has also been …
Parathyroid carcinoma: a review
RP Owen, CE Silver, PK Pellitteri, AR Shaha… - Head & …, 2011 - Wiley Online Library
Background. Parathyroid carcinoma is a rare entity, comprising fewer than 1% of cases of
hyperparathyroidism. The disease generally presents with severe hyperparathyroidism and …
hyperparathyroidism. The disease generally presents with severe hyperparathyroidism and …
Mechanisms of genotoxicity of nucleoside reverse transcriptase inhibitors
OA Olivero - Environmental and molecular mutagenesis, 2007 - Wiley Online Library
Nucleoside analogs were first approved by the US Food and Drug Administration for use
against HIV‐AIDS in 1987. Since then, these agents, now commonly referred to as …
against HIV‐AIDS in 1987. Since then, these agents, now commonly referred to as …
Highly active antiretroviral therapy drug combination induces oxidative stress and mitochondrial dysfunction in immortalized human blood–brain barrier endothelial …
The era of highly active antiretroviral therapy (HAART) has controlled AIDS and its related
disorders considerably; however, the prevalence of HIV-1-associated neurocognitive …
disorders considerably; however, the prevalence of HIV-1-associated neurocognitive …