Lyme disease in humans
JD Radolf, K Strle, JE Lemieux, F Strle - Current issues in molecular …, 2021 - mdpi.com
Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …
Lyme disease pathogenesis
Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …
Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes
In little more than 30 years, Lyme disease, which is caused by the spirochaete Borrelia
burgdorferi, has risen from relative obscurity to become a global public health problem and a …
burgdorferi, has risen from relative obscurity to become a global public health problem and a …
Protein acetylation dynamics in response to carbon overflow in Escherichia coli
B Schilling, D Christensen, R Davis… - Molecular …, 2015 - Wiley Online Library
In E scherichia coli, acetylation of proteins at lysines depends largely on a non‐enzymatic
acetyl phosphate‐dependent mechanism. To assess the functional significance of this post …
acetyl phosphate‐dependent mechanism. To assess the functional significance of this post …
The unique paradigm of spirochete motility and chemotaxis
Spirochete motility is enigmatic: It differs from the motility of most other bacteria in that the
entire bacterium is involved in translocation in the absence of external appendages. Using …
entire bacterium is involved in translocation in the absence of external appendages. Using …
Gene Regulation in Borrelia burgdorferi
DS Samuels - Annual review of microbiology, 2011 - annualreviews.org
Borrelia burgdorferi, the spirochete that causes Lyme disease, is maintained in nature via an
enzootic cycle that comprises a tick vector and a vertebrate host. Transmission from the tick …
enzootic cycle that comprises a tick vector and a vertebrate host. Transmission from the tick …
Stage‐specific global alterations in the transcriptomes of L yme disease spirochetes during tick feeding and following mammalian host adaptation
R Iyer, MJ Caimano, A Luthra, D Axline Jr… - Molecular …, 2015 - Wiley Online Library
B orrelia burgdorferi, the agent of L yme disease, is maintained in nature within an enzootic
cycle involving a mammalian reservoir and an I xodes sp. tick vector. The transmission …
cycle involving a mammalian reservoir and an I xodes sp. tick vector. The transmission …
Gene regulation and transcriptomics
Borrelia (Borreliella) burgdorferi, along with closely related species, is the etiologic agent of
Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition …
Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition …
Interaction of the Lyme disease spirochete with its tick vector
MJ Caimano, D Drecktrah, F Kung… - Cellular …, 2016 - Wiley Online Library
Borrelia burgdorferi, the causative agent of Lyme disease (along with closely related
genospecies), is in the deeply branching spirochete phylum. The bacterium is maintained in …
genospecies), is in the deeply branching spirochete phylum. The bacterium is maintained in …
Cyclic di-GMP is essential for the survival of the Lyme disease spirochete in ticks
Cyclic dimeric GMP (c-di-GMP) is a bacterial second messenger that modulates many
biological processes. Although its role in bacterial pathogenesis during mammalian infection …
biological processes. Although its role in bacterial pathogenesis during mammalian infection …