Structural and functional complexities of the mammalian lung evolved to meet a unique set
of challenges, namely, the provision of efficient delivery of inspired air to all lung units within …

It is well established that women exhibit several anatomic and physiologic characteristics
that distinguish their responses to exercise from those of men. These factors have been …

Background: Tissue iron depletion may negatively affect endurance performance and
muscle fatigability. Objective: We investigated tissue-level iron depletion and progressive …

The combined effects of hyperventilation and arterial desaturation on cerebral oxygenation
(Sc O 2) were determined using near-infrared spectroscopy. Eleven competitive oarsmen …

This study utilized a hypobaric chamber to compare the effects of mild hypobaria (MH; 50
mmHg, approximately 580 m altitude) on blood O2 status and maximal O2 consumption …

The cardiopulmonary exercise test (CPET) is an important physiological investigation that
can aid clinicians in their evaluation of exercise intolerance and dyspnea. Maximal oxygen …

During exercise, healthy individuals are able to maintain arterial oxygenation, whereas
highly-trained endurance athletes may exhibit an exercise-induced arterial hypoxaemia …

In young, healthy people the alveolar–arterial P difference (A‐aDO2) is small at rest, but
frequently increases during exercise. Previously, investigators have focused on …

Peak aerobic power in humans () is markedly affected by inspired O2 tension (). The
question to be answered in this study is what factor plays a major role in the limitation of …

Exercise‐induced arterial hypoxaemia is defined as a reduction in the arterial O2 pressure
(PaO2) by more than 1 kPa and/or a haemoglobin O2 saturation (SaO2) below 95%. With …