Multicellular tumor spheroids (MCTS) as a 3D in vitro evaluation tool of nanoparticles

H Lu, MH Stenzel - Small, 2018 - Wiley Online Library
Multicellular tumor spheroid models (MCTS) are often coined as 3D in vitro models that can
mimic the microenvironment of tissues. MCTS have gained increasing interest in the nano …

Carbohydrate ligands-directed active tumor targeting of combinatorial chemotherapy/phototherapy-based nanomedicine: A review

MM Agwa, H Elmotasem, H Elsayed… - International Journal of …, 2023 - Elsevier
Phototherapies or light mediated therapies, including mutually photothermal and
photodynamic therapy that encompass irradiation of the target organs with light, have been …

Targeting strategies for the combination treatment of cancer using drug delivery systems

J Kydd, R Jadia, P Velpurisiva, A Gad, S Paliwal, P Rai - Pharmaceutics, 2017 - mdpi.com
Cancer cells have characteristics of acquired and intrinsic resistances to chemotherapy
treatment—due to the hostile tumor microenvironment—that create a significant challenge …

Albumin nanoscience: homing nanotechnology enabling targeted drug delivery and therapy

S Lamichhane, S Lee - Archives of pharmacal research, 2020 - Springer
Albumin is a biocompatible, non-immunogenic and versatile drug carrier system. It has been
widely used to extend the half-life, enhance stability, provide protection from degradation …

Basic principles of drug delivery systems–the case of paclitaxel

S Ezrahi, A Aserin, N Garti - Advances in colloid and interface science, 2019 - Elsevier
Cancer is the second cause of death worldwide, exceeded only by cardiovascular diseases.
The prevalent treatment currently used against metastatic cancer is chemotherapy. Among …

The use of nanotechnology to combat liver cancer: Progress and perspectives

KJ Mintz, RM Leblanc - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2021 - Elsevier
Liver cancer is one of the most common cancers worldwide and is also one of the most
difficult cancers to treat, resulting in almost one million deaths per year, and the danger of …

Curcumin in the treatment of liver cancer: From mechanisms of action to nanoformulations

SI Shelash Al‐Hawary… - Phytotherapy …, 2023 - Wiley Online Library
Liver cancer is the sixth most prevalent cancer and ranks third in cancer‐related death, after
lung and colorectal cancer. Various natural products have been discovered as alternatives …

Celastrol-loaded lactosylated albumin nanoparticles attenuate hepatic steatosis in non-alcoholic fatty liver disease

N Fan, J Zhao, W Zhao, X Zhang, Q Song… - Journal of Controlled …, 2022 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease with several liver-
associated pathologic characteristics such as aberrant lipid accumulation, persistent chronic …

Antitumor effects of quercetin in hepatocarcinoma in vitro and in vivo models: a systematic review

P Fernández-Palanca, F Fondevila, C Méndez-Blanco… - Nutrients, 2019 - mdpi.com
Quercetin is a flavonoid present in fruits, vegetables and plants with antioxidant, anti-
inflammatory and anticancer properties. Its beneficial activities have been demonstrated in …

Combined phototherapy with metabolic reprogramming-targeted albumin nanoparticles for treating breast cancer

XT Le, J Lee, NT Nguyen, WT Lee, ES Lee… - Biomaterials …, 2022 - pubs.rsc.org
Triple-negative breast cancer (TNBC) is characterized by rapid tumor growth and resistance
to cancer therapy, and has a poor prognosis. Accumulating data have revealed that cancer …