[HTML][HTML] Inflammation and aging: signaling pathways and intervention therapies
Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …
[HTML][HTML] The landscape of aging
Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …
[HTML][HTML] The aging lung: Physiology, disease, and immunity
JL Schneider, JH Rowe, C Garcia-de-Alba, CF Kim… - Cell, 2021 - cell.com
The population is aging at a rate never seen before in human history. As the number of
elderly adults grows, it is imperative we expand our understanding of the underpinnings of …
elderly adults grows, it is imperative we expand our understanding of the underpinnings of …
[HTML][HTML] Mechanisms of lung aging
C Brandenberger, C Mühlfeld - Cell and tissue research, 2017 - Springer
Lung aging is associated with structural remodeling, a decline of respiratory function and a
higher susceptibility to acute and chronic lung diseases. Individual factors that modulate …
higher susceptibility to acute and chronic lung diseases. Individual factors that modulate …
[HTML][HTML] Immunosenescence, inflammaging, and lung senescence in asthma in the elderly
T Soma, M Nagata - Biomolecules, 2022 - mdpi.com
Prevalence of asthma in older adults is growing along with increasing global life expectancy.
Due to poor clinical consequences such as high mortality, advancement in understanding …
Due to poor clinical consequences such as high mortality, advancement in understanding …
Role of autophagy in lung diseases and ageing
Y Zhang, J Zhang, Z Fu - European Respiratory Review, 2022 - Eur Respiratory Soc
The lungs face ongoing chemical, mechanical, biological, immunological and xenobiotic
stresses over a lifetime. Advancing age progressively impairs lung function. Autophagy is a …
stresses over a lifetime. Advancing age progressively impairs lung function. Autophagy is a …
[HTML][HTML] Biomarkers of aging
Aging Biomarker Consortium, H Bao, J Cao… - Science China Life …, 2023 - Springer
Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …
The aging lung: is lung health good health for older adults?
DME Bowdish - Chest, 2019 - Elsevier
The prevalence of lung conditions, such as COPD and pulmonary fibrosis, and lung
infections, such as pneumonia, increases sharply with age. The physiologic, cellular, and …
infections, such as pneumonia, increases sharply with age. The physiologic, cellular, and …
[HTML][HTML] The contribution of oxidative stress and inflamm-aging in human and equine asthma
Aging is associated with a dysregulation of the immune system, leading to a general pro-
inflammatory state of the organism, a process that has been named inflamm-aging …
inflammatory state of the organism, a process that has been named inflamm-aging …
[HTML][HTML] Respiratory infections in the aging lung: implications for diagnosis, therapy, and prevention
A Häder, N Köse-Vogel, L Schulz, L Mlynska… - Aging and …, 2023 - ncbi.nlm.nih.gov
Respiratory infections pose a significant health problem among elderly individuals,
particularly during the COVID-19 pandemic. The increased mortality and morbidity rates …
particularly during the COVID-19 pandemic. The increased mortality and morbidity rates …