[PDF][PDF] Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma

AS Parikh, A Wizel, D Davis, A Lefranc-Torres… - Cell reports, 2022 - cell.com
Salivary adenoid cystic carcinoma (ACC) is a rare, biologically unique biphasic tumor that
consists of malignant myoepithelial and luminal cells. MYB and Notch signaling have been …

MuSCs and IPCs: roles in skeletal muscle homeostasis, aging and injury

H Jiang, B Liu, J Lin, T Xue, Y Han, C Lu… - Cellular and Molecular …, 2024 - Springer
Skeletal muscle is a highly specialized tissue composed of myofibres that performs crucial
functions in movement and metabolism. In response to external stimuli and injuries, a range …

[HTML][HTML] Cardiac stem cells: Current knowledge and future prospects

RA Mehanna, MM Essawy, MA Barkat… - World journal of stem …, 2022 - ncbi.nlm.nih.gov
Regenerative medicine is the field concerned with the repair and restoration of the integrity
of damaged human tissues as well as whole organs. Since the inception of the field several …

IGF-1 therapy improves muscle size and function in experimental peripheral arterial disease

G Dong, C Moparthy, T Thome, K Kim, F Yue… - Basic to Translational …, 2023 - jacc.org
Lower-extremity peripheral arterial disease (PAD) has increased in prevalence, yet
therapeutic development has remained stagnant. Skeletal muscle health and function has …

[HTML][HTML] Macrophages upregulate mural cell-like markers and support healing of ischemic injury by adopting functions important for vascular support

C Amoedo-Leite, K Parv, C Testini… - Nature Cardiovascular …, 2024 - nature.com
Sterile inflammation after injury is important for tissue restoration. In injured human and
mouse tissues, macrophages were recently found to accumulate perivascularly. This study …

CD146 expression profile in human skin and pre-vascularized dermo-epidermal skin substitutes in vivo

M Nanni, D Rütsche, C Bächler, L Pontiggia… - Journal of Biological …, 2023 - Springer
Background CD146 is a cell adhesion molecule whose expression profile in human skin has
not yet been elucidated. Here, we characterize CD146 expression pattern in human skin, in …

Optimization of a pericyte therapy to improve muscle recovery after limb immobilization

YF Wu, S Lapp, S Dvoretskiy… - Journal of Applied …, 2022 - journals.physiology.org
Extended bed rest or limb immobilization can significantly reduce skeletal muscle mass and
function. Recovery may be incomplete, particularly in older adults. Our laboratory recently …

[HTML][HTML] Approaches for the isolation and long-term expansion of pericytes from human and animal tissues

VV Alvino, KAK Mohammed, Y Gu… - Frontiers in …, 2023 - frontiersin.org
Pericytes surround capillaries in every organ of the human body. They are also present
around the vasa vasorum, the small blood vessels that supply the walls of larger arteries and …

Cell Therapy of Severe Ischemia in People with Diabetic Foot Ulcers—Do We Have Enough Evidence?

M Dubský, J Husáková, D Sojáková, V Fejfarová… - Molecular Diagnosis & …, 2023 - Springer
This current opinion article critically evaluates the efficacy of autologous cell therapy (ACT)
for chronic limb-threatening ischemia (CLTI), especially in people with diabetes who are not …

Injury/ischemia-induced stem cells: up-to-date knowledge and future perspectives for neural regeneration

T Nakagomi - Neural Regeneration Research, 2025 - journals.lww.com
Brain injuries like ischemic stroke induce endogenous stem cell production. Although the
precise traits of stem cells in pathological brains remain unclear, we previously …