The anti-inflammatory and immunomodulatory activities of natural products to control autoimmune inflammation

KD Moudgil, SH Venkatesha - International journal of molecular sciences, 2022 - mdpi.com
Inflammation is an integral part of autoimmune diseases, which are caused by dysregulation
of the immune system. This dysregulation involves an imbalance between pro-inflammatory …

Immunomodulatory, anti-inflammatory, and anti-cancer properties of ginseng: a pharmacological update

JA Valdés-González, M Sánchez, I Moratilla-Rivera… - Molecules, 2023 - mdpi.com
Ginseng, a medicinal plant of the genus Panax, boasts a rich historical record of usage that
dates back to the Paleolithic period. This botanical is extensively acknowledged and …

Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis

N Yang, M Li, L Wu, Y Song, S Yu, Y Wan… - Journal of …, 2023 - Springer
Macrophage polarization determines the production of cytokines that fuel the initiation and
evolution of rheumatoid arthritis (RA). Thus, modulation of macrophage polarization might …

Long noncoding RNA/circular RNA regulates competitive endogenous RNA networks in rheumatoid arthritis: molecular mechanisms and traditional Chinese medicine …

J Wen, J Liu, L Wan, F Wang - Annals of medicine, 2023 - Taylor & Francis
Rheumatoid arthritis (RA) is a systemic and autoimmune disease that is mainly featured
abnormal fibroblast-like synoviocyte (FLS) proliferation and inflammatory cell infiltration …

Clinical evidence construction of East Asian herbal medicine for inflammatory pain in rheumatoid arthritis based on integrative data mining approach

HG Jo, J Seo, D Lee - Pharmacological Research, 2022 - Elsevier
Background Rheumatoid arthritis (RA) is a chronic inflammatory disease that leads to a
significant social burden. East Asian herbal medicine (EAHM) has long been used to treat …

Efficacy and safety of dietary polyphenols in rheumatoid arthritis: A systematic review and meta-analysis of 47 randomized controlled trials

Z Long, W Xiang, Q He, W Xiao, H Wei, H Li… - Frontiers in …, 2023 - frontiersin.org
Objective To evaluate safety and efficacy of dietary polyphenols in the treatment of
rheumatoid arthritis (RA). Methods CNKI, Pubmed, Cochrane library, Embase were …

[HTML][HTML] Resveratrol as a privileged molecule with antioxidant activity

T Constantinescu, AG Mihis - Food Chemistry Advances, 2023 - Elsevier
Oxidative stress has a significant impact on the occurrence of many chronic diseases.
Antioxidants have ability to prevent, postpone or treat effects of free radicals. Resveratrol is a …

Triterpenes as potential drug candidates for rheumatoid arthritis treatment

C Faustino, L Pinheiro, N Duarte - Life, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease characterized by
joint inflammation, swelling and pain. Although RA mainly affects the joints, the disease can …

CCL21/CCR7 axis as a therapeutic target for autoimmune diseases

L Han, L Zhang - International Immunopharmacology, 2023 - Elsevier
Abstract Chemokine receptor 7 (CCR7) is a G protein-coupled receptor containing 7
transmembrane domains that is expressed on various cells, such as naive T/B cells, central …

Nutrients and rheumatoid arthritis: From the perspective of neutrophils

YR Shao, DY Xu, J Lin - Frontiers in Immunology, 2023 - frontiersin.org
Neutrophils are considered as core immune cells involve in the early stage of rheumatoid
arthritis (RA) and participate in the disease progression. The underlining mechanisms …