[HTML][HTML] Exploitation of glycosylation in enveloped virus pathobiology

Y Watanabe, TA Bowden, IA Wilson… - Biochimica et Biophysica …, 2019 - Elsevier
Glycosylation is a ubiquitous post-translational modification responsible for a multitude of
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to …

Newcastle disease virus at the forefront of cancer immunotherapy

B Burman, G Pesci, D Zamarin - Cancers, 2020 - mdpi.com
Simple Summary Newcastle disease virus (NDV) is an RNA virus belonging to the
Paramyxoviridae family. In nature, NDV primarily infects birds, but poses no threat to human …

Review detection of Newcastle disease virus

Q Mao, S Ma, PL Schrickel, P Zhao, J Wang… - Frontiers in Veterinary …, 2022 - frontiersin.org
Newcastle disease (ND) is an acute and highly contagious disease caused by the
Newcastle disease virus (NDV) infecting poultry, which has caused great harm to the poultry …

The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis

A Buschiazzo, MF Amaya, ML Cremona, AC Frasch… - Molecular cell, 2002 - cell.com
Trans-sialidases (TS) are GPI-anchored surface enzymes expressed in specific
developmental stages of trypanosome parasites like Trypanosoma cruzi, the etiologic agent …

[HTML][HTML] Structure and function of a paramyxovirus fusion protein

TG Morrison - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2003 - Elsevier
Paramyxoviruses initiate infection by attaching to cell surface receptors and fusing viral and
cell membranes. Viral attachment proteins, hemagglutinin-neuraminidase (HN) …

Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III

MC Lawrence, NA Borg, VA Streltsov, PA Pilling… - Journal of molecular …, 2004 - Elsevier
The three-dimensional structure of the haemagglutinin-neuraminidase (HN) from a human
parainfluenza virus is described at ca 2.0 Å resolution, both in native form and in complex …

Second sialic acid binding site in Newcastle disease virus hemagglutinin-neuraminidase: implications for fusion

V Zaitsev, M von Itzstein, D Groves, M Kiefel… - Journal of …, 2004 - Am Soc Microbiol
Paramyxoviruses are the leading cause of respiratory disease in children. Several
paramyxoviruses possess a surface glycoprotein, the hemagglutinin-neuraminidase (HN) …

Role of the hemagglutinin-neuraminidase protein in the mechanism of paramyxovirus-cell membrane fusion

T Takimoto, GL Taylor, HC Connaris… - Journal of …, 2002 - Am Soc Microbiol
Paramyxovirus infects cells by initially attaching to a sialic acid-containing cellular receptor
and subsequently fusing with the plasma membrane of the cells. Hemagglutinin …

Learning from the viral journey: how to enter cells and how to overcome intracellular barriers to reach the nucleus

D Mudhakir, H Harashima - The AAPS journal, 2009 - Springer
Viruses deliver their genome into host cells where they subsequently replicate and multiply.
A variety of relevant strategies have evolved by which viruses gain intracellular access and …

The HN protein of Newcastle disease virus induces cell apoptosis through the induction of lysosomal membrane permeabilization

Y Chen, S Zhu, T Liao, C Wang, J Han, Z Yang… - Plos …, 2024 - journals.plos.org
Lysosomes are acidic organelles that mediate the degradation and recycling of cellular
waste materials. Damage to lysosomes can cause lysosomal membrane permeabilization …