This biannual review covers the time period from January 2004 to December 2005 and is
written in continuation of previous reviews (A1-A3). An electronic search in SciFinder and …

Molecular beacons (MBs) are specifically designed DNA hairpin structures that are widely
used as fluorescent probes. Applications of MBs range from genetic screening, biosensor …

Fluorescence resonance energy transfer (FRET) is widely used in biomedical research as a
reporter method. Oligonucleotides with a DNA backbone and one or several chromophore …

Biosensors have witnessed an escalating interest nowadays, both in the research and
commercial fields. Deoxyribonucleic acid (DNA) biosensors (genosensors) have been …

We report the development of the multiplexed nanoflare, a nanoparticle agent that is
capable of simultaneously detecting two distinct mRNA targets inside a living cell. These …

Remarkable developments can be seen in the field of optical fibre biosensors in the last
decade. More sensors for specific analytes have been reported, novel sensing chemistries …

We build off the previously described concept of a nanoflare to develop an oligonucleotide
gold nanoparticle conjugate that is capable of both detecting and regulating intracellular …

We demonstrate the optical detection of DNA hybridization on the surface of solution
suspended single-walled carbon nanotubes (SWNTs) through a SWNT band gap …

Molecular beacon DNA probes, containing 1− 4 pyrene monomers on the 5 'end and the
quencher DABCYL on the 3 'end, were engineered and employed for real-time probing of …

The specific structural features of stem-loop (hairpin) DNA constructs provide increased
specificity of target recognition. Recently, several robust assays have been developed that …