Eukaryotic nucleosomes organize chromatin by wrapping 147 bp of DNA around a histone
core particle comprising two molecules each of histone H2A, H2B, H3 and H4. The DNA …

Centromeres are the eukaryotic chromosomal sites at which the kinetochore forms and
attaches to spindle microtubules to orchestrate chromosomal segregation in mitosis and …

Centromeres are specialized chromosome loci that seed the kinetochore, a large protein
complex that effects chromosome segregation. A 16-subunit complex, the constitutive …

The centromere performs a universally conserved function, to accurately partition genetic
information upon cell division. Yet, centromeres are among the most rapidly evolving …

Members of the order Mucorales may cause severe invasive fungal infections
(mucormycosis) in immune-compromised and otherwise ill patients. Diagnosis of Mucorales …

Here we review how evolving species concepts have been applied to understand yeast
diversity. Initially, a phenotypic species concept was utilized taking into consideration …

RNA interference (RNAi) was discovered at the end of last millennium, changing the way
scientists understood regulation of gene expression. Within the following two decades, a …

The classification of Mucorales encompasses a collection of basal fungi that have
traditionally demonstrated an aversion to modern genetic manipulation techniques. This …

The tremendous diversity in eukaryotic life forms can ultimately be traced back to
evolutionary modifications at the level of molecular networks. Deep understanding of these …

The order Mucorales is a group of ancient fungi with limited tools for gene manipulation. The
main consequence of this manipulation unwillingness is the limited knowledge about its …