Emerging role of artificial intelligence in diagnosis, classification and clinical management of glioma

J Luo, M Pan, K Mo, Y Mao, D Zou - Seminars in Cancer Biology, 2023 - Elsevier
Glioma represents a dominant primary intracranial malignancy in the central nervous
system. Artificial intelligence that mainly includes machine learning, and deep learning …

Treatment response and prognosis evaluation in high‐grade glioma: an imaging review based on MRI

Q Zhou, C Xue, X Ke, J Zhou - Journal of Magnetic Resonance …, 2022 - Wiley Online Library
In recent years, the development of advanced magnetic resonance imaging (MRI)
technology and machine learning (ML) have created new tools for evaluating treatment …

Targeted immunoimaging of tumor‐associated macrophages in orthotopic glioblastoma by the NIR‐IIb nanoprobes

H Zhu, F Ren, T Wang, Z Jiang, Q Sun, Z Li - Small, 2022 - Wiley Online Library
Developing dynamic and highly sensitive methods for imaging M2‐type tumor‐associated
macrophages (TAMs) is vital for monitoring the tumor progression and assessing the …

Immune infiltrating cells-derived risk signature based on large-scale analysis defines immune landscape and predicts immunotherapy responses in glioma tumor …

N Zhang, H Zhang, Z Wang, Z Dai, X Zhang… - Frontiers in …, 2021 - frontiersin.org
The glioma tumor microenvironment (TME), composed of several noncancerous cells and
biomolecules is known for its complexity of cancer-immune system interaction. Given that …

Characterization of fatty acid metabolism-related genes landscape for predicting prognosis and aiding immunotherapy in glioma patients

F Jiang, F Luo, N Zeng, Y Mao, X Tang… - Frontiers in …, 2022 - frontiersin.org
Glioma is a highly malignant brain tumor with a poor survival rate. The involvement of fatty
acid metabolism in glioma was examined to find viable treatment options. The information …

JMJD8 is an M2 macrophage biomarker, and it associates with DNA damage repair to facilitate stemness maintenance, chemoresistance, and immunosuppression in …

X Liang, H Zhang, Z Wang, X Zhang, Z Dai… - Frontiers in …, 2022 - frontiersin.org
Background JMJD8 has recently been identified as a cancer-related gene, but current
studies provide limited information. We aimed to clarify its roles and the potential …

Exploring the role of m6A methylation regulators in glioblastoma multiforme and their impact on the tumor immune microenvironment

X Deng, X Sun, Z Hu, Y Wu, C Zhou, J Sun… - The FASEB …, 2023 - Wiley Online Library
Although the role of N6‐Methyladenosine (m6A) methylation factors has been established in
multiple cancer types, its involvement in glioblastoma multiforme (GBM) remains limited …

CD74 correlated with malignancies and immune microenvironment in gliomas

S Xu, X Li, L Tang, Z Liu, K Yang… - Frontiers in molecular …, 2021 - frontiersin.org
Background: Cluster of differentiation 74 (CD74) is found to be highly involved in the
development of various types of cancers and could affect the activities of infiltrated cells in …

The CXCL family contributes to immunosuppressive microenvironment in gliomas and assists in gliomas chemotherapy

Z Wang, Y Liu, Y Mo, H Zhang, Z Dai, X Zhang… - Frontiers in …, 2021 - frontiersin.org
Gliomas are a type of malignant central nervous system tumor with poor prognosis.
Molecular biomarkers of gliomas can predict glioma patient's clinical outcome, but their …

A comprehensive prognostic signature for glioblastoma patients based on transcriptomics and single cell sequencing

F Fan, H Zhang, Z Dai, Y Zhang, Z Xia, H Cao, K Yang… - Cellular Oncology, 2021 - Springer
Purpose Glioblastoma (GBM) is the most common and deadly brain tumor. We aimed to
reveal potential prognostic GBM marker genes, elaborate their functions, and build an …