Over the past decade, in vivo gene replacement therapy has significantly advanced,
resulting in market approval of numerous therapeutics predominantly relying on adeno …

Transfer ribonucleic acid (tRNA) therapeutics will provide personalized and mutation
specific medicines to treat human genetic diseases for which no cures currently exist. The …

The NLRP3 inflammasome is a crucial component of the innate immune system, playing a
pivotal role in initiating and regulating the body's inflammatory response to various …

The NLRP3 inflammasome, a multiprotein complex responsible for triggering the release of
pro-inflammatory cytokines, plays a crucial role in inducing the inflammatory response …

Understanding the stability of mRNA loaded lipid nanoparticles (mRNA-LNPs) is imperative
for their clinical development. Herein, we propose the use of size-exclusion chromatography …

The health of the reproductive system is intricately linked to female fertility and quality of life.
There has been a growing prevalence of reproductive system disorders among women …

Nanomedicine has inspired a ground-breaking strategy for cancer therapy. By intelligently
assembling diverse moieties to form nanoparticles, numerous functionalities such as …

Lipid nanoparticles (LNPs) are commonly employed for drug delivery owing to their
considerable drug-loading capacity, low toxicity, and excellent biocompatibility …

Due to its versatility in formulation and manufacturing, self-emulsifying drug delivery systems
(SEDDS) can be used to design parenteral formulations. Therefore, it is necessary to …

Metastatic melanoma is a highly aggressive tumor with a poor prognosis. One of the
therapeutic options for patients bearing BRAF V600E mutations is targeted therapy, which is …