Immunotherapy aiming at suppressing tumor development by relying on modifying or
strengthening the immune system prevails among cancer treatments and points out a new …

Abstract B7-H3 (CD276), a member of the B7 family of proteins, is a key player in cancer
progression. This immune checkpoint molecule is selectively expressed in both tumor cells …

Immunotherapy for cancer is a rapidly developing treatment that modifies the immune
system and enhances the antitumor immune response. B7-H3 (CD276), a member of the B7 …

Immune checkpoint molecules, including inhibitory and stimulatory immune checkpoint
molecules, are defined as ligand–receptor pairs that exert inhibitory or stimulatory effects on …

Although the role of PD-L1 in suppressing the anti-tumor immune response is extensively
documented, recent discoveries indicate a distinct tumor-intrinsic role for PD-L1 in …

PD-L1 is overexpressed in tumor cells and contributes to cancer immunoevasion. However,
the role of the tumor cell-intrinsic PD-L1 in cancers remains unknown. Here we show that PD …

B7H3 (also known as CD276, an immune checkpoint molecule) is aberrantly overexpressed
in many types of cancer, and such upregulation is generally associated with a poor clinical …

Gastric cancer (GC), with a heterogeneous nature, is the third leading cause of death
worldwide. Over the past few decades, stable reductions in the incidence of GC have been …

Targeting the anti-tumor immune response via the B7 family of immune-regulatory
checkpoint proteins has revolutionized cancer treatment and resulted in punctuated …

Disulfidptosis and immune checkpoint genes play an important role in tumor treatment. But
there has been less research on the relationship between disulfidptosis and immune …