Objectives Second primary cancer is a common event in patients with head and neck
squamous cell carcinoma. However, the incidence and relevant factors vary by studies. We …

Purpose/objectives The increasing survivorship of head and neck squamous cell carcinoma
(HNSCC) comes with a risk of death from other causes, known as competing causes. The …

Importance Second primary malignant neoplasms (SPMNs) are the leading cause of death
in survivors of head and neck squamous cell carcinoma (HNSCC). Recently, human …

Concurrent chemoradiotherapy (CCRT) is the standard approach for the treatment of locally
advanced head and neck squamous cell carcinoma. Despite its undisputed advantages …

BACKGROUND Prognostic lymph node yield thresholds have been identified and
incorporated into treatment guidelines for multiple cancer sites, but not for oral cancer. The …

Purpose To compare a novel generalized competing event (GCE) model versus the
standard Cox proportional hazards regression model for stratifying elderly patients with …

Purpose The use of excessive and inappropriate medications is a common problem in
elderly populations. The use of polypharmacy (PP) and potentially inappropriate medication …

Background With improved cancer survivorship, cardiovascular disease (CVD) and other
noncancer events compete with cancer as the underlying cause of death, but the risks of …

Background The purpose of this study was to identify the prevalence of cancer cachexia and
its prognostic impact in patients with advanced head and neck squamous cell carcinoma …

BACKGROUND The current study was performed to characterize trends and survival
outcomes for chemotherapy in the definitive and adjuvant treatment of hypopharyngeal …