Neural functions of hypothalamic oxytocin and its regulation

P Wang, SC Wang, X Liu, S Jia, X Wang, T Li… - ASN …, 2022 - journals.sagepub.com
Oxytocin (OT), a nonapeptide, has a variety of functions. Despite extensive studies on OT
over past decades, our understanding of its neural functions and their regulation remains …

Oxytocin in neurodevelopmental disorders: Autism spectrum disorder and Prader-Willi syndrome

A Josselsohn, Y Zhao, D Espinoza… - Pharmacology & …, 2024 - Elsevier
This manuscript reviews recent work on oxytocin and its use in neurodevelopmental
disorders including spectrum disorder (ASD) and Prader-Willi syndrome (PWS). Oxytocin is …

Role of oxytocin in different neuropsychiatric, neurodegenerative, and neurodevelopmental disorders

AA Ghazy, OA Soliman, AI Elbahnasi, AY Alawy… - Reviews of physiology …, 2022 - Springer
Oxytocin has recently gained significant attention because of its role in the pathophysiology
and management of dominant neuropsychiatric disorders. Oxytocin, a peptide hormone …

Evaluating the neuropeptide–social cognition link in ageing: the mediating role of basic cognitive skills

R Polk, M Horta, T Lin, E Porges… - … of the Royal …, 2022 - royalsocietypublishing.org
The roles of oxytocin (OT) and arginine-vasopressin (AVP) as crucial modulators of social
cognition and related behaviours have been extensively addressed in the literature. The …

Oxytocin as a treatment for high-risk psychosis or early stages of psychosis: a mini review

SI Bargiota, AV Papakonstantinou… - Frontiers in …, 2023 - frontiersin.org
Individuals at clinical high risk for psychosis (CHR-P) present as help-seeking individuals
with social deficits as well as cognitive and functional impairment and have a 23–36% risk of …

Effects of four-week intranasal oxytocin administration on large-scale brain networks in older adults

P Liu, T Lin, H Fischer, D Feifel, NC Ebner - Neuropharmacology, 2024 - Elsevier
Oxytocin (OT) is a crucial modulator of social cognition and behavior. Previous work
primarily examined effects of acute intranasal oxytocin administration (IN-OT) in younger …

Effects of chronic intranasal oxytocin on visual attention to faces vs. natural scenes in older adults

A Shoenfelt, D Pehlivanoglu, T Lin, M Ziaei… - …, 2024 - Elsevier
Aging is associated with changes in face processing, including desensitization to face cues
like gaze direction and an attentional preference to faces with positive over negative …

Intranasal oxytocin suppresses seizure-like behaviors in a mouse model of NGLY1 deficiency

Y Makita, M Asahina, R Fujinawa, H Yukitake… - Communications …, 2024 - nature.com
NGLY1 deficiency is a genetic disease caused by biallelic mutations of the Ngly1 gene.
Although epileptic seizure is one of the most severe symptoms in patients with NGLY1 …

Four-week intranasal oxytocin administration reduces attachment avoidance in older women

KA Wright, R Polk, T Lin, D Feifel, NC Ebner - Hormones and behavior, 2023 - Elsevier
The neuropeptide oxytocin (OT) serves as a critical modulator of social cognition and social
behavior. Adult attachment is an affiliative process crucial for social interaction across …

Potential role of oxytocin in the regulation of memories and treatment of memory disorders

V Walia, P Wal, S Mishra, A Agrawal, S Kosey, AD Patil - Peptides, 2024 - Elsevier
Oxytocin (OXT) is an “affiliative” hormone or neurohormone or neuropeptide consists of nine
amino acids, synthesized in magnocellular neurons of paraventricular (PVN) and supraoptic …