[HTML][HTML] Nanotechnology-based delivery of CRISPR/Cas9 for cancer treatment
Abstract CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats-
associated protein 9) is a potent technology for gene-editing. Owing to its high specificity …
associated protein 9) is a potent technology for gene-editing. Owing to its high specificity …
Epithelial‐to‐mesenchymal transition in oral squamous cell carcinoma: challenges and opportunities
Z Ling, B Cheng, X Tao - International journal of cancer, 2021 - Wiley Online Library
Oral squamous cell carcinoma (OSCC) is the most common malignancy representing 90%
of all forms of oral cancer worldwide. Although great efforts have been made in the past …
of all forms of oral cancer worldwide. Although great efforts have been made in the past …
Structural insight and development of EGFR tyrosine kinase inhibitors
T Amelia, RE Kartasasmita, T Ohwada, DH Tjahjono - Molecules, 2022 - mdpi.com
Lung cancer has a high prevalence, with a growing number of new cases and mortality
every year. Furthermore, the survival rate of patients with non-small-cell lung carcinoma …
every year. Furthermore, the survival rate of patients with non-small-cell lung carcinoma …
Molecular targeting of epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR)
Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor
(VEGFR) are two extensively studied membrane-bound receptor tyrosine kinase proteins …
(VEGFR) are two extensively studied membrane-bound receptor tyrosine kinase proteins …
The universe of galectin-binding partners and their functions in health and disease
MF Troncoso, MT Elola, AG Blidner, L Sarrias… - Journal of Biological …, 2023 - ASBMB
Galectins, a family of evolutionarily conserved glycan-binding proteins, play key roles in
diverse biological processes including tissue repair, adipogenesis, immune cell …
diverse biological processes including tissue repair, adipogenesis, immune cell …
Next-generation EGFR tyrosine kinase inhibitors to overcome C797S mutation in non-small cell lung cancer (2019–2024)
D Das, L Xie, J Hong - RSC Medicinal Chemistry, 2024 - pubs.rsc.org
Lung cancer is a leading cause of cancer-related deaths worldwide. Non-small cell lung
cancer (NSCLC) accounts for the major portion (80–85%) of all lung cancer cases …
cancer (NSCLC) accounts for the major portion (80–85%) of all lung cancer cases …
Implicative role of epidermal growth factor receptor and its associated signaling partners in the pathogenesis of Alzheimer's disease
Epidermal growth factor receptor (EGFR) plays a pivotal role in early brain development,
although its expression pattern declines in accordance with the maturation of the active …
although its expression pattern declines in accordance with the maturation of the active …
Natural tyrosine kinase inhibitors acting on the epidermal growth factor receptor: Their relevance for cancer therapy
Y Liang, T Zhang, J Zhang - Pharmacological Research, 2020 - Elsevier
Epidermal growth factor receptor (EGFR), also known as ErbB-1/HER-1, plays a key role in
the regulation of the cell proliferation, migration, differentiation, and survival. Since the …
the regulation of the cell proliferation, migration, differentiation, and survival. Since the …
Mechanisms of cancer inhibition by local anesthetics
Y Zhang, Y Jing, R Pan, K Ding, R Chen… - Frontiers in …, 2021 - frontiersin.org
The use of local anesthetics during surgical treatment of cancer patients is an important part
of perioperative analgesia. In recent years, it has been showed that local anesthetics can …
of perioperative analgesia. In recent years, it has been showed that local anesthetics can …
Advances in targeting EGFR allosteric site as anti-NSCLC therapy to overcome the drug resistance
Background The epidermal growth factor receptor (EGFR) inhibitors represent the first-line
therapy regimen for non-small cell lung cancer (NSCLC). Most of these inhibitors target the …
therapy regimen for non-small cell lung cancer (NSCLC). Most of these inhibitors target the …