Recent advances in natural antifungal flavonoids and their derivatives

YS Jin - Bioorganic & medicinal chemistry letters, 2019 - Elsevier
The resistance of pathogenic fungi and failure of drug therapy increased dramatically.
Numerous studies have reported the individual or synergistic antifungal potency of natural …

Chalcones: Versatile intermediates in heterocyclic synthesis

YN Nayak, SL Gaonkar, M Sabu - Journal of Heterocyclic …, 2023 - Wiley Online Library
Chalcones are a fascinating and well‐studied group of organic molecules. Synthesis of
chalcones has been one of the essential areas of organic synthesis over the last few …

Synthesis of vanillin derivatives with 1, 2, 3‐triazole fragments and evaluation of their fungicide and fungistatic activities

PAR Gazolla, AR de Aguiar, MCA Costa… - Archiv der …, 2023 - Wiley Online Library
Vanillin is the main component of natural vanilla extract and is responsible for its flavoring
properties. Besides its well‐known applications as an additive in food and cosmetics, it has …

2-Hydroxychalcone as a potent compound and photosensitizer against dermatophyte biofilms

NM Bila, CB Costa-Orlandi, CO Vaso… - Frontiers in Cellular …, 2021 - frontiersin.org
Dermatophytes, fungi that cause dermatophytosis, can invade keratinized tissues in humans
and animals. The biofilm-forming ability of these fungi was described recently, and it may be …

AIEE active novel red-emitting D-π-A phenothiazine chalcones displaying large Stokes shift, solvatochromism and “turn-on” reversible mechanofluorochromism

T Sachdeva, MD Milton - Dyes and Pigments, 2020 - Elsevier
In an effort to develop red light emitting, AIEE active potential mechanofluorochromic smart
materials, a series of novel D-π-A based phenothiazine chalcone derivatives was designed …

Synthesis, Antibacterial, and Antioxidant Activities of Thiazolyl‐Pyrazoline Schiff Base Hybrids: A Combined Experimental and Computational Study

D Zelelew, M Endale, Y Melaku, F Kedir… - Journal of …, 2022 - Wiley Online Library
Thiazole‐pyrazoline Schiff base hybrids have a broad range of pharmacological potential
with an ability to control the activity of numerous metabolic enzymes. In this work, a greener …

Synthesis and biological evaluation of novel pyrazoline derivatives containing indole skeleton as anti-cancer agents targeting topoisomerase II

Y Song, S Feng, J Feng, J Dong, K Yang, Z Liu… - European journal of …, 2020 - Elsevier
In order to develop potent anticaner agents, a novel series of 3-(1H-indol-3-yl)-2, 3, 3a, 4-
tetrahydrothiochromeno [4, 3-c] pyrazole derivatives were synthesized. Structures of all …

Chloride substitution on 2-hydroxy-3, 4, 6-trimethoxyphenylchalcones improves in vitro selectivity on Trypanosoma cruzi strain Y

EP Magalhães, NDB Gomes, TA De Freitas… - Chemico-Biological …, 2022 - Elsevier
Chagas disease is a disease that is emerging in North America and Europe countries.
Benznidazole is the main drug available, but it has high toxicity and low efficacy in the …

[PDF][PDF] Synthesis, characterization, and antibacterial activity of some new pyrimidine derivatives from chalcone derivatives

RW Adam, HMY Al-Labban, IN Kadhim… - Drug Invention …, 2019 - researchgate.net
Objectives: This research involves synthesis of some chalcones derivatives from
Acetophenone as starting material. Methods: The derivatives of chalcone compounds [Ch1 …

[HTML][HTML] Design, synthesis, bioactivity and mechanism of dithioacetal derivatives containing dioxyether moiety

Y Wang, J Zhang, F He, X Gan, B Song, D Hu - Bioorganic & Medicinal …, 2019 - Elsevier
The present work designed and synthesized a series of dithioacetal derivatives containing
dioxyether, as well as evaluated their antiviral activities against tobacco mosaic virus (TMV) …