Probiotics, like lactic acid bacteria, are non-pathogenic microbes that exert health benefits to
the host when administered in adequate quantity. Currently, research is being conducted on …

The complex polymicrobial composition of human gut microbiota plays a key role in health
and disease. Lachnospiraceae belong to the core of gut microbiota, colonizing the intestinal …

Liver steatosis without alcohol consumption, namely, nonalcoholic fatty liver disease
(NAFLD), is a common hepatic condition that encompasses a wide spectrum of …

Progressive liver fibrosis, induced by chronic viral and metabolic disorders, leads to more
than one million deaths annually via development of cirrhosis, although no antifibrotic …

The pathogenesis of non-alcoholic fatty liver disease, particularly the mechanisms whereby
a minority of patients develop a more severe phenotype characterised by hepatocellular …

NAFLD is currently the main cause of chronic liver disease in developed countries, and the
number of NAFLD patients is growing worldwide. NAFLD often has similar symptoms to …

The presence of advanced fibrosis in nonalcoholic fatty liver disease (NAFLD) is the most
important predictor of liver mortality. There are limited data on the diagnostic accuracy of gut …

Hepatocellular carcinoma (HCC) is the third leading cause of worldwide cancer mortality.
HCC almost exclusively develops in patients with chronic liver disease, driven by a vicious …

Bile acids facilitate intestinal nutrient absorption and biliary cholesterol secretion to maintain
bile acid homeostasis, which is essential for protecting liver and other tissues and cells from …

Several animal studies have emphasized the role of gut microbiota in nonalcoholic fatty liver
disease (NAFLD). However, data about gut dysbiosis in human NAFLD remain scarce in the …