Mesenchymal stem cells-derived exosomes for drug delivery

Y Sun, G Liu, K Zhang, Q Cao, T Liu, J Li - Stem cell research & therapy, 2021 - Springer
Exosomes are extracellular vesicles secreted by various cells, mainly composed of lipid
bilayers without organelles. In recent years, an increasing number of researchers have …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Mesenchymal stem cell-derived exosomes as new tools for delivery of miRNAs in the treatment of cancer

A Dalmizrak, O Dalmizrak - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Although ongoing medical research is working to find a cure for a variety of cancers, it
continues to be one of the major causes of death worldwide. Chemotherapy and …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles in Cancer Therapy Resistance: from Biology to Clinical Opportunity

C Shan, Y Liang, K Wang, P Li - International Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are a type of stromal cells characterized by their properties
of self-renewal and multi-lineage differentiation, which make them prominent in regenerative …

Adipose stem cells-released extracellular vesicles as a next-generation cargo delivery vehicles: a survey of minimal information implementation, mass production and …

J Chen, R Liu, T Huang, H Sun, H Jiang - Stem Cell Research & Therapy, 2022 - Springer
Objectives To investigate current situation of minimal information implementation highlighted
by minimal information for studies of extracellular vesicles 2018 (MISEV2018) guidelines …

Role of non-coding RNAs in neuroblastoma

AA Anoushirvani, A Jafarian Yazdi, S Amirabadi… - Cancer Gene …, 2023 - nature.com
Neuroblastoma is known as the most prevalent extracranial malignancy in childhood with a
neural crest origin. It has been widely accepted that non-coding RNAs (ncRNAs) play …

Mesenchymal stromal cells in neuroblastoma: exploring crosstalk and therapeutic implications

C Hochheuser, LJ Windt, NY Kunze… - Stem cells and …, 2021 - liebertpub.com
Neuroblastoma (NB) is the second most common solid cancer in childhood, accounting for
15% of cancer-related deaths in children. In high-risk NB patients, the majority suffers from …

Glioblastoma therapy: rationale for a mesenchymal stem cell-based vehicle to carry recombinant viruses

S Ali, Q Xia, T Muhammad, L Liu, X Meng… - Stem Cell Reviews and …, 2021 - Springer
Evasion of growth suppression is among the prominent hallmarks of cancer. Phosphatase
and tensin homolog (PTEN) and p53 tumor-suppressive pathways are compromised in most …

[HTML][HTML] Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targeting

AR Farina, LA Cappabianca, V Zelli… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
Pediatric neuroblastomas (NBs) are heterogeneous, aggressive, therapy-resistant
embryonal tumours that originate from cells of neural crest (NC) origin and in particular …

Exosomes as neurological nanosized machines

E Pishavar, M Trentini, F Zanotti… - ACS Nanoscience …, 2022 - ACS Publications
In the past few decades, nanomedicine research has advanced dramatically. In spite of this,
traditional nanomedicine faces major obstacles, such as blood–brain barriers, low …