Progress in biological age research
Z Li, W Zhang, Y Duan, Y Niu, Y Chen, X Liu… - Frontiers in public …, 2023 - frontiersin.org
Biological age (BA) is a common model to evaluate the function of aging individuals as it
may provide a more accurate measure of the extent of human aging than chronological age …
may provide a more accurate measure of the extent of human aging than chronological age …
Functional genomics data: privacy risk assessment and technological mitigation
The generation of functional genomics data by next-generation sequencing has increased
greatly in the past decade. Broad sharing of these data is essential for research …
greatly in the past decade. Broad sharing of these data is essential for research …
Association of unhealthy lifestyle and childhood adversity with acceleration of aging among UK biobank participants
G Yang, X Cao, X Li, J Zhang, C Ma, N Zhang… - JAMA network …, 2022 - jamanetwork.com
Importance Accelerated aging makes adults more vulnerable to chronic diseases and death.
Whether childhood adversity is associated with accelerated aging processes, and to what …
Whether childhood adversity is associated with accelerated aging processes, and to what …
Role of sleep quality in the acceleration of biological aging and its potential for preventive interaction on air pollution insults: Findings from the UK Biobank cohort
Sleep has been associated with aging and relevant health outcomes, but the causal
relationship remains inconclusive. In this study, we investigated the associations of sleep …
relationship remains inconclusive. In this study, we investigated the associations of sleep …
Proteomic aging clock (PAC) predicts age‐related outcomes in middle‐aged and older adults
Beyond mere prognostication, optimal biomarkers of aging provide insights into qualitative
and quantitative features of biological aging and might, therefore, offer useful information for …
and quantitative features of biological aging and might, therefore, offer useful information for …
ExplaiNAble BioLogical Age (ENABL Age): an artificial intelligence framework for interpretable biological age
Background Biological age is a measure of health that offers insights into ageing. The
existing age clocks, although valuable, often trade off accuracy and interpretability. We …
existing age clocks, although valuable, often trade off accuracy and interpretability. We …
Longitudinal fundus imaging and its genome-wide association analysis provide evidence for a human retinal aging clock
Biological age, distinct from an individual's chronological age, has been studied extensively
through predictive aging clocks. However, these clocks have limited accuracy in short time …
through predictive aging clocks. However, these clocks have limited accuracy in short time …
[HTML][HTML] COVID-19 severity is predicted by earlier evidence of accelerated aging
With no known treatments or vaccine, COVID-19 presents a major threat, particularly to older
adults, who account for the majority of severe illness and deaths. The age-related …
adults, who account for the majority of severe illness and deaths. The age-related …
Accelerated aging mediates the associations of unhealthy lifestyles with cardiovascular disease, cancer, and mortality
X Li, X Cao, J Zhang, J Fu… - Journal of the …, 2024 - Wiley Online Library
Background With two well‐validated aging measures capturing mortality and morbidity risk,
this study examined whether and to what extent aging mediates the associations of …
this study examined whether and to what extent aging mediates the associations of …
Genetic loci and metabolic states associated with murine epigenetic aging
Abstract Changes in DNA methylation (DNAm) are linked to aging. Here, we profile highly
conserved CpGs in 339 predominantly female mice belonging to the BXD family for which …
conserved CpGs in 339 predominantly female mice belonging to the BXD family for which …