Has ferrocene really delivered its role in accentuating the bioactivity of organic scaffolds?

B Sharma, V Kumar - Journal of medicinal chemistry, 2021 - ACS Publications
Ferrocene is an important structural core in bioorganometallic chemistry because of its
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …

Triazole derivatives and their anti-tubercular activity

S Zhang, Z Xu, C Gao, QC Ren, L Chang, ZS Lv… - European journal of …, 2017 - Elsevier
Tuberculosis (TB) remains one of the most widespread and leading deadliest diseases,
threats one-third of the world's population. Although numerous efforts have been undertaken …

Isatin containing heterocycles for different biological activities: Analysis of structure activity relationship

R Nath, S Pathania, G Grover, MJ Akhtar - Journal of Molecular Structure, 2020 - Elsevier
Isatin has been widely used in drug discovery. The ring is part of many naturally occurring
compounds and is used to design compounds with diverse biological activities. These isatin …

A mini review on isatin, an anticancer scaffold with potential activities against neglected tropical diseases (NTDs)

S Chowdhary, Shalini, A Arora, V Kumar - Pharmaceuticals, 2022 - mdpi.com
Isatin, chemically an indole-1 H-2, 3-dione, is recognised as one of the most attractive
therapeutic fragments in drug design and development. The template has turned out to be …

Emerging impact of triazoles as anti-tubercular agent

A Sharma, AK Agrahari, S Rajkhowa… - European Journal of …, 2022 - Elsevier
Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

Ferrocene derivatives as anti-infective agents

BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …

Synthesis, antimicrobial, antibiofilm and computational studies of isatin-semicarbazone tethered 1, 2, 3-triazoles

A Kumar, K Lal, V Kumar, M Murtaza, S Jaglan… - Bioorganic …, 2023 - Elsevier
In present era, heterocyclic compounds containing two or three nitrogen atoms play a vital
role in drug discovery. In this context, a new class of isatin-semicarbazone tethered 1, 2, 3 …

Bioactive 1, 2, 3‐Triazoles: An Account on their Synthesis, Structural Diversity and Biological Applications

L da SM Forezi, CGS Lima, AAP Amaral… - The Chemical …, 2021 - Wiley Online Library
The triazole heterocycle is a privileged scaffold in medicinal chemistry, since its structure is
present in a large number of biologically active molecules, including several drugs currently …

5-Fluoro-1H-indole-2, 3-dione-triazoles-synthesis, biological activity, molecular docking, and DFT study

S Deswal, RK Tittal, DG Vikas, K Lal, A Kumar - Journal of Molecular …, 2020 - Elsevier
An environmental friendly heterogeneous catalyst Cell-CuI-NPs was employed for the
synthesis of biologically promising 1-((1-aryl)-1H-1, 2, 3-triazol-4-yl) methyl-5-fluoroindoline …

[HTML][HTML] Recent advances in chalcone-triazole hybrids as potential pharmacological agents

A Bhukal, V Kumar, L Kumar, K Lal - Results in Chemistry, 2023 - Elsevier
Molecular hybridization is one of the recent strategies to synthesize a novel hybrid
compound by combining two or more pharmacophoric units. Being a linkage process, it …