Has ferrocene really delivered its role in accentuating the bioactivity of organic scaffolds?
Ferrocene is an important structural core in bioorganometallic chemistry because of its
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …
Triazole derivatives and their anti-tubercular activity
S Zhang, Z Xu, C Gao, QC Ren, L Chang, ZS Lv… - European journal of …, 2017 - Elsevier
Tuberculosis (TB) remains one of the most widespread and leading deadliest diseases,
threats one-third of the world's population. Although numerous efforts have been undertaken …
threats one-third of the world's population. Although numerous efforts have been undertaken …
Isatin containing heterocycles for different biological activities: Analysis of structure activity relationship
R Nath, S Pathania, G Grover, MJ Akhtar - Journal of Molecular Structure, 2020 - Elsevier
Isatin has been widely used in drug discovery. The ring is part of many naturally occurring
compounds and is used to design compounds with diverse biological activities. These isatin …
compounds and is used to design compounds with diverse biological activities. These isatin …
A mini review on isatin, an anticancer scaffold with potential activities against neglected tropical diseases (NTDs)
Isatin, chemically an indole-1 H-2, 3-dione, is recognised as one of the most attractive
therapeutic fragments in drug design and development. The template has turned out to be …
therapeutic fragments in drug design and development. The template has turned out to be …
Emerging impact of triazoles as anti-tubercular agent
A Sharma, AK Agrahari, S Rajkhowa… - European Journal of …, 2022 - Elsevier
Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …
Ferrocene derivatives as anti-infective agents
BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
Synthesis, antimicrobial, antibiofilm and computational studies of isatin-semicarbazone tethered 1, 2, 3-triazoles
In present era, heterocyclic compounds containing two or three nitrogen atoms play a vital
role in drug discovery. In this context, a new class of isatin-semicarbazone tethered 1, 2, 3 …
role in drug discovery. In this context, a new class of isatin-semicarbazone tethered 1, 2, 3 …
Bioactive 1, 2, 3‐Triazoles: An Account on their Synthesis, Structural Diversity and Biological Applications
L da SM Forezi, CGS Lima, AAP Amaral… - The Chemical …, 2021 - Wiley Online Library
The triazole heterocycle is a privileged scaffold in medicinal chemistry, since its structure is
present in a large number of biologically active molecules, including several drugs currently …
present in a large number of biologically active molecules, including several drugs currently …
5-Fluoro-1H-indole-2, 3-dione-triazoles-synthesis, biological activity, molecular docking, and DFT study
An environmental friendly heterogeneous catalyst Cell-CuI-NPs was employed for the
synthesis of biologically promising 1-((1-aryl)-1H-1, 2, 3-triazol-4-yl) methyl-5-fluoroindoline …
synthesis of biologically promising 1-((1-aryl)-1H-1, 2, 3-triazol-4-yl) methyl-5-fluoroindoline …
[HTML][HTML] Recent advances in chalcone-triazole hybrids as potential pharmacological agents
Molecular hybridization is one of the recent strategies to synthesize a novel hybrid
compound by combining two or more pharmacophoric units. Being a linkage process, it …
compound by combining two or more pharmacophoric units. Being a linkage process, it …