Tocopherols and tocotrienols—bioactive dietary compounds; what is certain, what is doubt?

K Szewczyk, A Chojnacka, M Górnicka - International journal of molecular …, 2021 - mdpi.com
Tocopherols and tocotrienols are natural compounds of plant origin, available in the nature.
They are supplied in various amounts in a diet, mainly from vegetable oils, some oilseeds …

Vitamin E: regulatory redox interactions

T Miyazawa, GC Burdeos, M Itaya, K Nakagawa… - IUBMB …, 2019 - Wiley Online Library
Vitamin E is an essential nutrient that was discovered in the 1920s. Many of the
physiological functions of vitamin E, including its antioxidative effects, have been studied for …

Vitamin E therapy beyond cancer: Tocopherol versus tocotrienol

HY Peh, WSD Tan, W Liao, WSF Wong - Pharmacology & therapeutics, 2016 - Elsevier
The discovery of vitamin E (α-tocopherol) began in 1922 as a vital component required in
reproduction. Today, there are eight naturally occurring vitamin E isoforms, namely α-, β-, γ …

Pharmacological potential of tocotrienols: a review

H Ahsan, A Ahad, J Iqbal, WA Siddiqui - Nutrition & metabolism, 2014 - Springer
Tocotrienols, members of the vitamin E family, are natural compounds found in a number of
vegetable oils, wheat germ, barley, and certain types of nuts and grains. Like tocopherols …

Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases

BB Aggarwal, C Sundaram, S Prasad… - Biochemical …, 2010 - Elsevier
Initially discovered in 1938 as a “fertility factor,” vitamin E now refers to eight different
isoforms that belong to two categories, four saturated analogues (α, β, γ, and δ) called …

The implication of reactive oxygen species and antioxidants in knee osteoarthritis

NB Tudorachi, EE Totu, A Fifere, V Ardeleanu… - Antioxidants, 2021 - mdpi.com
Knee osteoarthritis (KOA) is a chronic multifactorial pathology and a current and essential
challenge for public health, with a negative impact on the geriatric patient's quality of life …

Cancer-preventive activities of tocopherols and tocotrienols

J Ju, SC Picinich, Z Yang, Y Zhao, N Suh… - …, 2010 - academic.oup.com
The cancer-preventive activity of vitamin E has been studied. Whereas some
epidemiological studies have suggested a protective effect of vitamin E against cancer …

The impact of antioxidant agents complimentary to periodontal therapy on oxidative stress and periodontal outcomes: A systematic review

FWMG Muniz, SB Nogueira, FLV Mendes… - Archives of oral …, 2015 - Elsevier
There is significant evidence linking chronic periodontitis (CP) and oxidative stress (OS). CP
is a multifactorial infecto-inflammatory disease caused by the interaction of microbial agents …

Vitamins and bone health: beyond calcium and vitamin D

H Ahmadieh, A Arabi - Nutrition Reviews, 2011 - academic.oup.com
Osteoporosis is a major health disorder associated with an increased risk of fracture.
Nutrition is among the modifiable factors that influence the risk of osteoporosis and fracture …

The role of vitamin E in preventing and treating osteoarthritis–a review of the current evidence

KY Chin, S Ima-Nirwana - Frontiers in pharmacology, 2018 - frontiersin.org
Osteoarthritis is a debilitating disease of the joint involving cartilage degeneration and
chondrocytes apoptosis. Oxidative stress is one of the many proposed mechanisms …