Growth hormone-secreting pituitary adenomas that cause acromegaly arise as monoclonal
expansions of differentiated somatotroph cells and are usually sporadic. They are almost …

Purpose Non-functioning pituitary adenomas (NFPAs) are associated with impaired well-
being, increased comorbidities, and reduced long-term survival. Data on optimal …

The primary treatment for brain tumors often involves surgical resection for diagnosis, relief
of mass effect, and prolonged survival. In neurosurgery, it is of utmost importance to achieve …

Purpose Surgical experience is considered paramount for excellent outcome of
transsphenoidal surgery (TSS). However, objective data demonstrating the surgical success …

Context The tumor immune microenvironment is associated with clinical outcomes and
immunotherapy responsiveness. Objective To investigate the intratumoral immune profile of …

OBJECTIVE Given the anatomical complexity and frequently invasive growth of giant
pituitary adenomas (GPAs), individually tailored approaches are required. The aim of this …

Endoscopic pituitary surgery has shown promising results. This study reports the
experiences of experienced microscopic pituitary surgeons changing to the endoscopic …

OBJECTIVE For symptomatic nonsecreting pituitary adenomas (PAs), resection remains a
critical option for treatment. In this study, the authors used a large-population national …

Introduction The optimal surgical treatment for giant pituitary neuroendocrine tumors
(GPitNETs) is debated. Research question The aim of this paper is to optimize the surgical …

Objective The European Reference Network on Rare Endocrine Conditions (Endo-ERN)
aims to organize high-quality healthcare throughout Europe, including care for pituitary …