Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond

Y Lee, E Puumala, N Robbins, LE Cowen - Chemical reviews, 2020 - ACS Publications
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …

Worldwide emergence of fluconazole-resistant Candida parapsilosis: current framework and future research roadmap

F Daneshnia, JN de Almeida Júnior, M Ilkit… - The Lancet …, 2023 - thelancet.com
Candida parapsilosis is one of the most commen causes of life-threatening candidaemia,
particularly in premature neonates, individuals with cancer of the haematopoietic system …

COVID-19-associated candidiasis (CAC): an underestimated complication in the absence of immunological predispositions?

A Arastehfar, A Carvalho, MH Nguyen, MT Hedayati… - Journal of fungi, 2020 - mdpi.com
The recent global pandemic of COVID-19 has predisposed a relatively high number of
patients to acute respiratory distress syndrome (ARDS), which carries a risk of developing …

Twenty Years of the SENTRY Antifungal Surveillance Program: Results for Candida Species From 1997–2016

MA Pfaller, DJ Diekema, JD Turnidge… - Open forum …, 2019 - academic.oup.com
Background The emergence of antifungal resistance threatens effective treatment of
invasive fungal infection (IFI). Invasive candidiasis is the most common health care …

[HTML][HTML] Invasive candidiasis

PG Pappas, MS Lionakis, MC Arendrup… - Nature Reviews …, 2018 - nature.com
Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

Fungal endocarditis: pathophysiology, epidemiology, clinical presentation, diagnosis, and management

GR Thompson III, JD Jenks, JW Baddley… - Clinical microbiology …, 2023 - Am Soc Microbiol
Fungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated
with high morbidity and mortality (> 70%), and presents numerous challenges during clinical …

Rezafungin versus caspofungin for treatment of candidaemia and invasive candidiasis (ReSTORE): a multicentre, double-blind, double-dummy, randomised phase 3 …

GR Thompson, A Soriano, OA Cornely, BJ Kullberg… - The Lancet, 2023 - thelancet.com
Background Rezafungin is a next-generation, once-a-week echinocandin in development
for the treatment of candidaemia and invasive candidiasis and for the prevention of invasive …

Diagnosis and treatment of invasive candidiasis

N Barantsevich, E Barantsevich - Antibiotics, 2022 - mdpi.com
Candida species, belonging to commensal microbial communities in humans, cause
opportunistic infections in individuals with impaired immunity. Pathogens encountered in …

Candida auris: a review of the literature

A Jeffery-Smith, SK Taori, S Schelenz… - Clinical microbiology …, 2018 - Am Soc Microbiol
The emerging pathogen Candida auris has been associated with nosocomial outbreaks on
five continents. Genetic analysis indicates the simultaneous emergence of separate clades …

Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment

MC Arendrup, TF Patterson - The Journal of infectious diseases, 2017 - academic.oup.com
Invasive Candida infections remain an important cause of morbidity and mortality, especially
in hospitalized and immunocompromised or critically ill patients. A limited number of …