Fibromyalgia: an update on clinical characteristics, aetiopathogenesis and treatment

P Sarzi-Puttini, V Giorgi, D Marotto… - Nature Reviews …, 2020 - nature.com
Fibromyalgia is characterized by chronic widespread pain, fatigue, sleep disturbances and
functional symptoms. The etiopathogenesis, diagnostic criteria and classification criteria of …

Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities

KD Davis, N Aghaeepour, AH Ahn, MS Angst… - Nature Reviews …, 2020 - nature.com
Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …

Building better biomarkers: brain models in translational neuroimaging

CW Woo, LJ Chang, MA Lindquist, TD Wager - Nature neuroscience, 2017 - nature.com
Despite its great promise, neuroimaging has yet to substantially impact clinical practice and
public health. However, a developing synergy between emerging analysis techniques and …

[HTML][HTML] AAPT diagnostic criteria for fibromyalgia

LM Arnold, RM Bennett, LJ Crofford, LE Dean… - The journal of pain, 2019 - Elsevier
Fibromyalgia (FM) is a common chronic pain disorder that presents diagnostic challenges
for clinicians. Several classification, diagnostic and screening criteria have been developed …

Common and stimulus-type-specific brain representations of negative affect

M Čeko, PA Kragel, CW Woo, M López-Solà… - Nature …, 2022 - nature.com
The brain contains both generalized and stimulus-type-specific representations of aversive
events, but models of how these are integrated and related to subjective experience are …

Brain imaging tests for chronic pain: medical, legal and ethical issues and recommendations

KD Davis, H Flor, HT Greely, GD Iannetti… - Nature Reviews …, 2017 - nature.com
Chronic pain is the greatest source of disability globally and claims related to chronic pain
feature in many insurance and medico-legal cases. Brain imaging (for example, functional …

Composite pain biomarker signatures for objective assessment and effective treatment

I Tracey, CJ Woolf, NA Andrews - Neuron, 2019 - cell.com
Pain is a subjective sensory experience that can, mostly, be reported but cannot be directly
measured or quantified. Nevertheless, a suite of biomarkers related to mechanisms, neural …

Representation, pattern information, and brain signatures: from neurons to neuroimaging

PA Kragel, L Koban, LF Barrett, TD Wager - Neuron, 2018 - cell.com
Human neuroimaging research has transitioned from mapping local effects to developing
predictive models of mental events that integrate information distributed across multiple …

Emotion regulation and the salience network: a hypothetical integrative model of fibromyalgia

AM Pinto, R Geenen, TD Wager, MA Lumley… - Nature Reviews …, 2023 - nature.com
Fibromyalgia is characterized by widespread pain, fatigue, sleep disturbances and other
symptoms, and has a substantial socioeconomic impact. Current biomedical and …

[HTML][HTML] Brain (re) organisation following amputation: Implications for phantom limb pain

TR Makin, H Flor - Neuroimage, 2020 - Elsevier
Following arm amputation the region that represented the missing hand in primary
somatosensory cortex (S1) becomes deprived of its primary input, resulting in changed …