Background: Tendon disorders increasingly afflict our aging society but we lack the scientific
understanding to clinically address them. Clinically relevant models of tendon disease are …

Abstract In his Lissner Award medal lecture in 2000, Stephen Cowin asked the
question:“How is a tissue built?” It is not a new question, but it remains as relevant today as it …

Tendon is a dense connective tissue that stores and transmits forces between muscles and
bones. Cellular heterogeneity is increasingly recognized as an important factor in the …

Tendon injuries heal via a scar-mediated response, and there are no biological approaches
to promote more regenerative healing. Mouse flexor tendons heal through the formation of …

The molecular events that drive post‐natal tendon development are poorly characterized. In
this study, we profiled morphological, mechanical, and transcriptional changes in the rat …

Scleraxis is a basic helix-loop-helix transcription factor that plays a central role in promoting
tenocyte proliferation and matrix synthesis during embryonic tendon development. However …

Tendons perform a critical function in the musculoskeletal system by integrating muscle with
skeleton and enabling force transmission. Damage or degeneration of these tissues leads to …

Tendon harbors a cell population that possesses stem cell characteristics such as
clonogenicity, multipotency and self-renewal capacity, commonly referred to as tendon …

Skeletal muscle contraction is essential for the movement of our musculoskeletal system.
Tendons and ligaments that connect the skeletal muscles to bones in the correct position at …

Tendons are specialized matrix‐rich connective tissues that transmit forces from muscle to
bone and are essential for movement. As tissues that frequently transfer large mechanical …