Pedunculopontine nucleus region deep brain stimulation (DBS) is a promising but
experimental therapy for axial motor deficits in Parkinson's disease (PD), particularly gait …

In the last quarter of a century, DBS has become an established neurosurgical treatment for
Parkinson's disease (PD), dystonia, and tremors. Improved understanding of brain circuitries …

To assess the impact of Parkinson's disease (PD) on spontaneous discourse, we conducted
computerized analyses of brief monologues produced by 51 patients and 50 controls. We …

Between 2005 and 2007, six patients affected by idiopathic Parkinson's disease (IPD) were
submitted to the bilateral implantation (and subsequent deep brain stimulation—DBS) of the …

Background: Serendipity and observations have a noble tradition in medicine, including
neurology, and are responsible for many medical treatments (carbamazepine for tic …

Abstract Parkinson's disease (PD), which involves the degeneration of dopaminergic
neurons in the basal ganglia, has long been associated with motor deficits. Increasing …

The interest in the pedunculopontine tegmental nucleus (PPTg), a structure located in the
brainstem at the level of the pontomesencephalic junction, has greatly increased in recent …

Several investigations have shown language impairments following electrode implantation
surgery for Deep Brain Stimulation (DBS) in movement disorders. The impact of the actual …

Improvement of gait disorders following pedunculopontine nucleus area stimulation in
patients with Parkinson's disease has previously been reported and led us to propose this …

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an efficacious therapy for
Parkinson's disease (PD) but its effects on non-motor facets may be detrimental. The low …