The functional capabilities of skeletal muscle are strongly correlated with its well-arranged
microstructure, consisting of parallelly aligned myotubes. In case of extensive muscle loss …

The extracellular matrix (ECM) is a complex, dynamic network present within all tissues and
organs that not only acts as a mechanical support and anchorage point but can also direct …

Directional cell migration plays a pivotal role in wound healing; however, traditional wound
management mainly focuses on providing permissive environment, less focused on …

Hydrogel has been an attractive biomaterial for tissue engineering, drug delivery, wound
healing, and contact lens materials, due to its outstanding properties, including high water …

Due to their mechanical and structural similarity to native tissues, hydrogel biomaterials
have gained tremendous popularity for applications in 3D tissue culture, therapeutic …

Intestinal stem cells (ISC) are crucial players in colon epithelium physiology. The accurate
control of their auto-renewal, proliferation and differentiation capacities provides a constant …

Abstract Myotonic dystrophy type 1 (DM1) is the most common hereditary myopathy in the
adult population. The disease is characterized by progressive skeletal muscle degeneration …

Diabetic ulcers remain a significant challenge in wound care due to loss of epithelial cell
migration. Aligned nanofibrous scaffolds mimicking the skin's extracellular matrix (ECM) are …

Background Mechanobiology in the field of human female reproduction has been extremely
challenging technically and ethically. Methods The present review provides the current …

Tissue engineering aims at replicating tissues and organs to develop applications in vivo
and in vitro. In vivo, by engineering artificial constructs using functional materials and cells to …