How can AI help improve food safety?
With advances in artificial intelligence (AI) technologies, the development and
implementation of digital food systems are becoming increasingly possible. There is …
implementation of digital food systems are becoming increasingly possible. There is …
Microbial polyketides and their roles in insect virulence: from genomics to biological functions
W Toopaang, W Bunnak, C Srisuksam… - Natural Product …, 2022 - pubs.rsc.org
Covering: May 1966 up to January 2022 Entomopathogenic microorganisms have potential
for biological control of insect pests. Their main secondary metabolites include polyketides …
for biological control of insect pests. Their main secondary metabolites include polyketides …
PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection
Disruption of cellular activities by pathogen virulence factors can trigger innate immune
responses. Interferon-γ (IFN-γ)–inducible antimicrobial factors, such as the guanylate …
responses. Interferon-γ (IFN-γ)–inducible antimicrobial factors, such as the guanylate …
Toxoplasma-proximal and distal control by GBPs in human macrophages
Human guanylate binding proteins (GBPs) are key players of interferon–gamma (IFNγ)-
induced cell intrinsic defense mechanisms targeting intracellular pathogens. In this study …
induced cell intrinsic defense mechanisms targeting intracellular pathogens. In this study …
Structural insights into the activation mechanism of antimicrobial GBP1
The dynamin-related human guanylate-binding protein 1 (GBP1) mediates host defenses
against microbial pathogens. Upon GTP binding and hydrolysis, auto-inhibited GBP1 …
against microbial pathogens. Upon GTP binding and hydrolysis, auto-inhibited GBP1 …
p97/VCP targets Toxoplasma gondii vacuoles for parasite restriction in interferon-stimulated human cells
Infection with the parasite Toxoplasma gondii leads to production of interferon gamma (IFNγ)
that stimulates cells to upregulate defense proteins targeting the parasite for cell intrinsic …
that stimulates cells to upregulate defense proteins targeting the parasite for cell intrinsic …
Online citizen science with the Zooniverse for analysis of biological volumetric data
P Smith, ONF King, A Pennington, W Tun… - Histochemistry and Cell …, 2023 - Springer
Public participation in research, also known as citizen science, is being increasingly
adopted for the analysis of biological volumetric data. Researchers working in this domain …
adopted for the analysis of biological volumetric data. Researchers working in this domain …
[HTML][HTML] Interaction of microbiota, mucosal malignancies, and immunotherapy-mechanistic insights
LF Mager, T Krause, KD McCoy - Mucosal Immunology, 2024 - Elsevier
The microbiome has emerged as a crucial modulator of host immune interactions and
clearly impacts on tumor development and therapy efficacy. The microbiome is a double …
clearly impacts on tumor development and therapy efficacy. The microbiome is a double …
OrgaMapper: a robust and easy-to-use workflow for analyzing organelle positioning
Background Eukaryotic cells are highly compartmentalized by a variety of organelles that
carry out specific cellular processes. The position of these organelles within the cell is …
carry out specific cellular processes. The position of these organelles within the cell is …
BetaBuddy: An automated end-to-end computer vision pipeline for analysis of calcium fluorescence dynamics in β-cells
Insulin secretion from pancreatic β-cells is integral in maintaining the delicate equilibrium of
blood glucose levels. Calcium is known to be a key regulator and triggers the release of …
blood glucose levels. Calcium is known to be a key regulator and triggers the release of …