Role of oxidative modifications in atherosclerosis

R Stocker, JF Keaney Jr - Physiological reviews, 2004 - journals.physiology.org
This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

Superoxide anion radical (O· 2), superoxide dismutases, and related matters

I Fridovich - Journal of biological chemistry, 1997 - ASBMB
A field of inquiry may be said to have come of age when conclusions initially viewed as
remarkable or even unbelievable are accepted as commonplace. Study of the biology of the …

Nitric oxide donors: chemical activities and biological applications

PG Wang, M Xian, X Tang, X Wu, Z Wen, T Cai… - Chemical …, 2002 - ACS Publications
Nitric Oxide Donors: Chemical Activities and Biological Applications | Chemical Reviews ACS
ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications …

Extracellular superoxide dismutase in biology and medicine

CL Fattman, LM Schaefer, TD Oury - Free Radical Biology and Medicine, 2003 - Elsevier
Accumulated evidence has shown that reactive oxygen species (ROS) are important
mediators of cell signaling events such as inflammatory reactions (superoxide) and the …

Oxidant and antioxidant balance in the airways and airway diseases

I Rahman, SK Biswas, A Kode - European journal of pharmacology, 2006 - Elsevier
Although oxygen is a prerequisite to life, at concentrations beyond the physiological limits it
may be hazardous to the cells. Since the lungs are directly exposed to very high amounts of …

Superoxide dismutases in the lung and human lung diseases

VL Kinnula, JD Crapo - American journal of respiratory and critical …, 2003 - atsjournals.org
The lungs are directly exposed to higher oxygen concentrations than most other tissues.
Increased oxidative stress is a significant part of the pathogenesis of obstructive lung …

Regulation of the cerebral circulation: role of endothelium and potassium channels

FM Faraci, DD Heistad - Physiological reviews, 1998 - journals.physiology.org
Faraci, Frank M., and Donald D. Heistad. Regulation of the Cerebral Circulation: Role of
Endothelium and Potassium Channels. Physiol. Rev. 78: 53–97, 1998.—Several new …

Superoxide dismutase 1 in health and disease: how a frontline antioxidant becomes neurotoxic

BG Trist, JB Hilton, DJ Hare, PJ Crouch… - Angewandte Chemie …, 2021 - Wiley Online Library
Cu/Zn superoxide dismutase (SOD1) is a frontline antioxidant enzyme catalysing superoxide
breakdown and is important for most forms of eukaryotic life. The evolution of aerobic …

Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

T Rangasamy, J Guo, WA Mitzner, J Roman… - The Journal of …, 2005 - rupress.org
Oxidative stress has been postulated to play an important role in the pathogenesis of
asthma; although a defect in antioxidant responses has been speculated to exacerbate …

Oxidative stress in allergic respiratory diseases

RP Bowler, JD Crapo - Journal of Allergy and Clinical Immunology, 2002 - Elsevier
There is ample evidence that allergic disorders, such as asthma, rhinitis, and atopic
dermatitis, are mediated by oxidative stress. Excessive exposure to reactive oxygen and …