Amiodarone is a potent antidysrhythmic agent that can cause potentially life-threatening
pulmonary fibrosis. Accumulating evidence has demonstrated that myofibroblast …

Background Amiodarone (AMD) and its metabolite N-desethylamiodarone can cause some
adverse effects, which include pulmonary toxicity. Some studies suggest that mitochondrial …

Methods and Results: 36 adult male albino rats were divided into 4 groups. Rats of AM
group were given 30 mg/kg daily orally for 4 weeks. Rats of IV SCT group were injected with …

Amiodarone (AD) is one of the most frequently prescribed anti‐arrhythmic agents worldwide,
but its effectiveness is limited due to the development of pulmonary toxicity. Several lines of …

Background: Chronic interstitial pneumonitis is the most common presentation of
amiodarone-induced pulmonary disease. Aim of the work: To throw a light on the damage of …

目的本研究探讨长期胺碘酮不同剂量对大鼠肺脏的影响. 方法随机选择雄性SD 大鼠30 只,
随机分为对照组(NC, n= 10), 胺碘酮低剂量组[n= 10, 50mg/(kg· d), AM50], 胺碘酮高剂量组[n …

Embora muitos avanços tenham sido realizados no âmbito da quimioterapia da doença de
Chagas nos últimos anos, ainda não há tratamento com perfil satisfatório de eficácia e …

Propósito y Método del Estudio: El propósito de este estudio fue determinar amiodarona y
desetilamiodarona en plasma y eritrocitos de pacientes con terapia crónica antiarrítmica y …

The invention relates to a compound selected from the group consisting of
desethylamiodarone and pharmaceutically acceptable salts, hydrates and solvates thereof …

RESUMO A amiodarona é um dos fármacos mais usados para o tratamento de arritmias
cardíacas, tanto ventriculares como supraventriculares. Apesar de sua eficácia, o uso da …