Abstract Background Nanomaterials (NMs) are often exposed to a broad range of
biomolecules of different abundances. Biomolecule sorption driven by various interfacial …

Atomic force spectroscopy (AFS) is one of the most promising and powerful tools to get
information on biorecognition processes at single molecule resolution. AFS allows to …

If all philosophy starts with wondering, then Calculated Surprises starts with wondering
about how computers are changing the face and inner workings of science. In this book …

Force spectroscopy measurements of the rupture of the molecular bond between biotin and
streptavidin often results in a wide distribution of rupture forces. We attribute the long tail of …

Cells in multicellular organisms adhere to the extracellular matrix through two-dimensional
clusters spanning a size range from very few to thousands of adhesion bonds. For many …

The physics of nanoscopic systems is strongly governed by thermal fluctuations that produce
significant deviations from the behaviour of large ensembles,. Stretching experiments of …

Single-molecule force spectroscopy has become a valuable tool for the investigation of
intermolecular energy landscapes for a wide range of molecular associations. Atomic force …

During the last decade, many authors took advantage of new methodologies based on
atomic force microscopy (AFM), biomembrane force probes (BFPs), laminar flow chambers …

The quantitative analysis of molecular interactions is of high interest in medical research.
Most methods for the investigation of ligand–receptor complexes deal with huge ensembles …

Atomic force spectroscopy has become a widely used technique for investigating forces,
energies, and dynamics of biomolecular interactions. These studies provide dissociation …