Eukaryotic genomes are pervasively transcribed. Besides protein-coding RNAs, there are
different types of non-coding RNAs that modulate complex molecular and cellular …

For decades, research into cancer biology focused on the involvement of protein-coding
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …

Here we present an extensive narrative review of the broadly understood modifications to
the lifestyles of women with polycystic ovary syndrome (PCOS). The PubMed database was …

There is a great deal of hype surrounding the concept of personalized medicine.
Personalized medicine is rooted in the belief that since individuals possess nuanced and …

Gynecologic cancers involve the female genital organs, such as the vulva, vagina, cervix,
endometrium, ovaries, and fallopian tubes. The occurrence and frequency of gynecologic …

Cancer is a disease of the genome caused by oncogene activation and tumor suppressor
gene inhibition. Deep sequencing studies including large consortia such as TCGA and …

Nm (2′-O-methylation) is one of the most common modifications in the RNA world. It has
the potential to influence the RNA molecules in multiple ways, such as structure, stability …

Background Breast cancer is one of the most common malignancies and the major cause of
cancer-related death in women. Although the importance of PIWI-interacting RNAs (piRNAs) …

With the first RNA interference (RNAi) drug (ONPATTRO (patisiran)) on the market, we
witness the RNAi therapy field reaching a critical turning point, when further improvements in …

Background Emerging evidence suggests that PIWI-interacting RNAs (piRNAs) may be
important epigenetic regulators of gene expression in human cancers; however, their …