Host–Parasite interactions in Entamoeba histolytica and Entamoeba dispar: what have we learned from their genomes?

IW Wilson, GD Weedall, N Hall - Parasite Immunology, 2012 - Wiley Online Library
Invasive amoebiasis caused by Entamoeba histolytica is a major global health problem.
Virulence is a rare outcome of infection, occurring in fewer than 1 in 10 infections. Not all …

AmoebaDB and MicrosporidiaDB: functional genomic resources for Amoebozoa and Microsporidia species

C Aurrecoechea, A Barreto, J Brestelli… - Nucleic acids …, 2010 - academic.oup.com
Abstract AmoebaDB (http://AmoebaDB. org) and MicrosporidiaDB (http://MicrosporidiaDB.
org) are new functional genomic databases serving the amoebozoa and microsporidia …

Design and utilization of epitope-based databases and predictive tools

N Salimi, W Fleri, B Peters, A Sette - Immunogenetics, 2010 - Springer
In the last decade, significant progress has been made in expanding the scope and depth of
publicly available immunological databases and online analysis resources, which have …

Systems-Level Metabolic Flux Profiling Elucidates a Complete, Bifurcated Tricarboxylic Acid Cycle in Clostridium acetobutylicum

D Amador-Noguez, XJ Feng, J Fan… - Journal of …, 2010 - Am Soc Microbiol
Obligatory anaerobic bacteria are major contributors to the overall metabolism of soil and
the human gut. The metabolic pathways of these bacteria remain, however, poorly …

Ergatis: a web interface and scalable software system for bioinformatics workflows

J Orvis, J Crabtree, K Galens, A Gussman… - …, 2010 - academic.oup.com
Motivation: The growth of sequence data has been accompanied by an increasing need to
analyze data on distributed computer clusters. The use of these systems for routine analysis …

Setting our bibliographic references free: towards open citation data

S Peroni, A Dutton, T Gray, D Shotton - Journal of Documentation, 2015 - emerald.com
Purpose–Citation data needs to be recognised as a part of the Commons–those works that
are freely and legally available for sharing–and placed in an open repository. The paper …

Novel Burkholderia mallei virulence factors linked to specific host-pathogen protein interactions

V Memišević, N Zavaljevski, R Pieper… - Molecular & Cellular …, 2013 - ASBMB
Burkholderia mallei is an infectious intracellular pathogen whose virulence and resistance to
antibiotics makes it a potential bioterrorism agent. Given its genetic origin as a commensal …

[HTML][HTML] Prioritizing drug targets in Clostridium botulinum with a computational systems biology approach

SA Muhammad, S Ahmed, A Ali, H Huang, X Wu… - Genomics, 2014 - Elsevier
A computational and in silico system level framework was developed to identify and
prioritize the antibacterial drug targets in Clostridium botulinum (Clb), the causative agent of …

Interrogation of the Burkholderia pseudomallei Genome to Address Differential Virulence among Isolates

JF Challacombe, CJ Stubben, CP Klimko, SL Welkos… - PLoS …, 2014 - journals.plos.org
Infection by the Gram-negative pathogen Burkholderia pseudomallei results in the disease
melioidosis, acquired from the environment in parts of southeast Asia and northern Australia …

Differential expression of small RNAs from Burkholderia thailandensis in response to varying environmental and stress conditions

CJ Stubben, SN Micheva-Viteva, Y Shou… - BMC genomics, 2014 - Springer
Abstract Background Bacterial small RNAs (sRNAs) regulate gene expression by base-
pairing with downstream target mRNAs to attenuate translation of mRNA into protein at the …