Cancer spheroids and organoids as novel tools for research and therapy: state of the art and challenges to guide precision medicine
S El Harane, B Zidi, N El Harane, KH Krause, T Matthes… - Cells, 2023 - mdpi.com
Spheroids and organoids are important novel players in medical and life science research.
They are gradually replacing two-dimensional (2D) cell cultures. Indeed, three-dimensional …
They are gradually replacing two-dimensional (2D) cell cultures. Indeed, three-dimensional …
The Tango between cancer-associated fibroblasts (CAFs) and immune cells in affecting immunotherapy efficacy in pancreatic cancer
I Stouten, N van Montfoort, LJAC Hawinkels - International Journal of …, 2023 - mdpi.com
The lack of response to therapy in pancreatic ductal adenocarcinoma (PDAC) patients has
contributed to PDAC having one of the lowest survival rates of all cancer types. The poor …
contributed to PDAC having one of the lowest survival rates of all cancer types. The poor …
Preclinical evaluation of the gorilla‐derived HAdV‐B AdV‐lumc007 oncolytic adenovirus 'GoraVir'for the treatment of pancreatic ductal adenocarcinoma
STF Bots, TJ Harryvan, C Groeneveldt… - Molecular …, 2024 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy which shows
unparalleled therapeutic resistance due to its genetic and cellular heterogeneity, dense …
unparalleled therapeutic resistance due to its genetic and cellular heterogeneity, dense …
Disfunction of communication among immune cells in minimal-deviation adenocarcinoma of the cervix as an immunotherapeutic opportunity
H Zhang, C Liu, X Zhai, Q Zhang, Y Zhou… - International …, 2023 - Elsevier
Minimal deviation adenocarcinoma (MDA) of the uterine cervix, also referred to as malignant
adenoma, is a rare subtype of cervical adenocarcinoma that exhibits histological …
adenoma, is a rare subtype of cervical adenocarcinoma that exhibits histological …
Cationic liposomes overcome neutralizing antibodies and enhance reovirus efficacy in ovarian cancer
Z Yang, L Chen, T Guo, L Huang, Y Yang, R Ye… - Virology, 2024 - Elsevier
Reovirus (Reo) has shown promising potential in specifically killing tumor cells, and offering
new possibilities for ovarian cancer (OC) treatment. However, neutralizing antibodies in the …
new possibilities for ovarian cancer (OC) treatment. However, neutralizing antibodies in the …
[HTML][HTML] Generation and characterization of mAb 61H9 against junctional adhesion molecule-a with potent antitumor activity
Junctional adhesion molecule-A (JAM-A) is an adhesion molecule that exists on the surface
of certain types of cells, including white blood cells, endothelial cells, and dendritic cells. In …
of certain types of cells, including white blood cells, endothelial cells, and dendritic cells. In …
[PDF][PDF] Preclinical evaluation of the gorilla-derived oncolytic adenovirus AdV-lumc007 “GoraVir” for the treatment of pancreatic ductal adenocarcinoma
STF Bots, T Harryvan, C Groeneveldt… - Mol …, 2022 - scholarlypublications …
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy which shows
unparalleled therapeutic resistance due to its genetic and cellular heterogeneity, dense …
unparalleled therapeutic resistance due to its genetic and cellular heterogeneity, dense …
TGFβ signaling in cancer-associated fibroblasts drives a hepatic gp130-dependent pro-metastatic inflammatory program in CMS4 colorectal cancer subtype
TJ Harryvan, S Abudukelimu, I Stouten, EJ van der Wel… - bioRxiv, 2024 - biorxiv.org
Current molecular classification of colorectal cancer (CRC), the Consensus Molecular
Subtypes (CMS), has highlighted the biological heterogeneity of CRC and enables patient …
Subtypes (CMS), has highlighted the biological heterogeneity of CRC and enables patient …