The neuroendocrinology of menopause is reviewed from a comparative perspective, with
emphasis on laboratory rodent models. These changes are compared by the 2011 STRAW …

Multiple theories exist to explain cancer initiation, although a consensus on this is crucial for
developing effective therapies.'Somatic mutation theory'suggests that mutations in somatic …

Platelets modulate clinically relevant yet incompletely understood tissue regeneration
processes, and platelet rich plasma (PRP) has been previously used with some success in …

Background Follicle stimulating hormone (FSH) exerts action on both germline and somatic
compartment in both ovary and testis although FSH receptors (FSHR) are localized only on …

For many years, ovarian biology has been based on the dogma that oocytes reserve in
female mammals included a finite number, established before or at birth and it is determined …

Female mammals are born with a fixed pool of germ cells, which does not replenish during
adult life. However, this has been recently challenged and adult ovaries produce oocytes …

OBJECTIVES: This work assessed sexual and neurobehavioral parameters after ovarian
treatment with autologous PRP. DESIGN: Questionnaire study. MATERIAL AND METHODS …

The transcriptional factor OCT4 regulates pluripotency of stem cells and has an important
role during oocyte growth. Whereas, its role has remained ambiguous in ovarian tissue …

The physiology of gamete development is at the core of understanding reproductive
medicine. In humans, oogenesis begins approximately 3 weeks after fertilization. Primordial …

Until recently, the mammalian ovary was considered to consist of fully differentiated tissues,
but evidence for the presence of adult stem cells in this organ appeared. The differentiation …