[HTML][HTML] Review and evolution of guidelines for diagnosis of COVID-19 vaccine induced thrombotic thrombocytopenia (VITT)

EJ Favaloro, L Pasalic, G Lippi - Clinical Chemistry and Laboratory …, 2022 - degruyter.com
Abstract Coronavirus disease 2019 (COVID-19) is a life-threatening infectious disease
caused by Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2). In response to …

Antibodies against platelet factor 4 and their associated pathologies: from HIT/HITT to spontaneous HIT-like syndrome, to COVID-19, to VITT/TTS

EJ Favaloro, L Pasalic, G Lippi - Antibodies, 2022 - mdpi.com
Antibodies against platelet factor 4 (PF4), a protein released from alpha-granules of
activated platelets, may cause a number of pathophysiological conditions. The most …

[HTML][HTML] Assessment of immunological anti‐platelet factor 4 antibodies for vaccine‐induced thrombotic thrombocytopenia (VITT) in a large Australian cohort: A …

EJ Favaloro, J Clifford, E Leitinger, M Parker… - Journal of Thrombosis …, 2022 - Elsevier
Background Vaccine‐induced thrombotic thrombocytopenia (VITT) is a rare complication of
adenovirus‐based vaccines aimed to prevent and minimize COVID‐19 and related …

[HTML][HTML] Risk-benefit analysis of the AstraZeneca COVID-19 vaccine in Australia using a Bayesian network modelling framework

CL Lau, HJ Mayfield, JE Sinclair, SJ Brown, M Waller… - Vaccine, 2021 - Elsevier
Abstract Thrombosis and Thrombocytopenia Syndrome (TTS) has been associated with the
AstraZencea (AZ) COVID-19 vaccine (Vaxzevria). Australia has reported low TTS incidence …

A novel flow cytometry procoagulant assay for diagnosis of vaccine-induced immune thrombotic thrombocytopenia

CSM Lee, HPH Liang, DE Connor, A Dey… - Blood …, 2022 - ashpublications.org
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe prothrombotic
complication of adenoviral vaccines, including the ChAdOx1 nCoV-19 (Vaxzevria) vaccine …

New insights into human immune memory from SARS‐CoV‐2 infection and vaccination

GE Hartley, ESJ Edwards, RE O'Hehir, MC van Zelm - Allergy, 2022 - Wiley Online Library
Since early 2020, the world has been embroiled in an ongoing viral pandemic with SARS‐
CoV‐2 and emerging variants resulting in mass morbidity and an estimated 6 million deaths …

Evolution of hemostasis testing: a personal reflection covering over 40 years of history

EJ Favaloro - Seminars in Thrombosis and Hemostasis, 2024 - thieme-connect.com
There is no certainty in change, other than change is certain. As Seminars in Thrombosis
and Hemostasis celebrates 50 years of publication, I felt it appropriate to reflect on my own …

D-dimer testing: A narrative review

L Wauthier, J Favresse, M Hardy, J Douxfils… - Advances in clinical …, 2023 - Elsevier
D-dimer containing species are soluble fibrin degradation products derived from plasmin-
mediated degradation of cross-linked fibrin, ie,'D-dimer'. D-dimer can hence be considered a …

Laboratory testing for platelet factor 4 antibodies: differential utility for diagnosis/exclusion of heparin induced thrombocytopenia versus suspected vaccine induced …

EJ Favaloro, L Pasalic, B Henry, G Lippi - Pathology, 2022 - Elsevier
Summary Platelet factor 4 (PF4), a protein stored in the alpha-granules of platelets and
released upon activation, forms cationic tetramers that bind with various polymeric anions …

Understanding vaccine‐induced thrombotic thrombocytopenia (VITT)

C Dix, J McFadyen, A Huang, S Chunilal… - Internal Medicine …, 2022 - Wiley Online Library
Vaccine‐induced thrombotic thrombocytopenia (VITT) is a rare, but serious, syndrome
characterised by thrombocytopenia, thrombosis, a markedly raised D‐dimer and the …