Novel orexin receptor agonists based on arene-or pyridine-fused 1, 3-dihydro-2H-imidazole-2-imines

W Wang, A Ranjan, W Zhang, Q Liang… - Bioorganic & Medicinal …, 2024 - Elsevier
A structurally novel class of benzo-or pyrido-fused 1, 3-dihydro-2H-imidazole-2-imines was
designed and evaluated in an inositol phosphate accumulation assay for G q signaling to …

Narcolepsy and rapid eye movement sleep

F Biscarini, L Barateau, F Pizza, G Plazzi… - Journal of Sleep …, 2024 - Wiley Online Library
Since the first description of narcolepsy at the end of the 19th Century, great progress has
been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the …