OBSERVE: guidelines for the refinement of rodent cancer models
SI De Vleeschauwer, M van de Ven, A Oudin… - Nature …, 2024 - nature.com
Existing guidelines on the preparation (Planning Research and Experimental Procedures on
Animals: Recommendations for Excellence (PREPARE)) and reporting (Animal Research …
Animals: Recommendations for Excellence (PREPARE)) and reporting (Animal Research …
Rac1 as a Target to Treat Dysfunctions and Cancer of the Bladder
V Sauzeau, J Beignet, C Bailly - Biomedicines, 2022 - mdpi.com
Bladder pathologies, very common in the aged population, have a considerable negative
impact on quality of life. Novel targets are needed to design drugs and combinations to treat …
impact on quality of life. Novel targets are needed to design drugs and combinations to treat …
Homogeneous polyporus polysaccharide inhibit bladder cancer by resetting tumor-associated macrophages toward m1 through nf-κb/nlrp3 signaling
C Liu, D He, S Zhang, H Chen, J Zhao, X Li… - Frontiers in …, 2022 - frontiersin.org
Bladder cancer (BC) is one of the most common urinary system tumors, which characterized
by a high incidence. Polyporus polysaccharide is the main active component of polyporus …
by a high incidence. Polyporus polysaccharide is the main active component of polyporus …
Preclinical models of bladder cancer: BBN and beyond
Preclinical modelling is a crucial component of advancing the understanding of cancer
biology and therapeutic development. Several models exist for understanding the …
biology and therapeutic development. Several models exist for understanding the …
Targeting microRNA-145-mediated progressive phenotypes of early bladder cancer in a molecularly defined in vivo model
K Heishima, N Sugito, C Abe, A Hirata, H Sakai… - … Therapy-Nucleic Acids, 2023 - cell.com
A progressive subclass of early-stage non-muscle-invasive bladder cancer (NMIBC)
frequently recurs and progress into invasive carcinoma, thus decreasing the overall survival …
frequently recurs and progress into invasive carcinoma, thus decreasing the overall survival …
A novel prognostic model based on three integrin subunit genes-related signature for bladder cancer
H Tu, H Liu, L Zhang, Z Tan, H Wang, Y Jiang… - Frontiers in …, 2022 - frontiersin.org
Background Presently, a comprehensive analysis of integrin subunit genes (ITGs) in bladder
cancer (BLCA) is absent. This study endeavored to thoroughly analyze the utility of ITGs in …
cancer (BLCA) is absent. This study endeavored to thoroughly analyze the utility of ITGs in …
[HTML][HTML] A pilot study on active and passive ex vivo characterisation of the urinary bladder and its impact on three-dimensional modelling
R Trostorf, EM Orcajo, A Pötzke, T Siebert… - journal of the mechanical …, 2022 - Elsevier
Insight into the global deformation of the urinary bladder during passive and active phases is
crucial for understanding the biomechanics and function of the organ. Therefore, in the …
crucial for understanding the biomechanics and function of the organ. Therefore, in the …
[HTML][HTML] Lead acetate versus cadmium sulfate in the modulation of main physiological pathways controlling detrusor muscle contractility in rat
Heavy metals have a deleterious effect on lower urinary tract functions. Scant data has been
reported about metals' effect on altering detrusor muscle contractility. Rats were given lead …
reported about metals' effect on altering detrusor muscle contractility. Rats were given lead …
DNA methylome changes of muscle-and neuronal-related processes precede bladder cancer invasiveness
Simple Summary Urinary bladder cancer can be therapeutically controlled until it becomes
invasive, thus identifying critical molecular processes preceding and promoting the transition …
invasive, thus identifying critical molecular processes preceding and promoting the transition …
[PDF][PDF] Rac1 as a Target to Treat Dysfunctions and Cancer of the Bladder. Biomedicines 2022, 10, 1357
V Sauzeau, J Beignet, C Bailly - 2022 - academia.edu
Bladder pathologies, very common in the aged population, have a considerable negative
impact on quality of life. Novel targets are needed to design drugs and combinations to treat …
impact on quality of life. Novel targets are needed to design drugs and combinations to treat …