Wound healing is a complex and dynamic biological process that involves the coordinated
efforts of multiple cell types and is executed and regulated by numerous growth factors and …

In the last few decades, a great deal of progress has been made in understanding the
cellular and biochemical interplay that comprises the normal wound healing response. This …

Background Diabetes mellitus continues to grow in global prevalence and to consume an
increasing amount of health care resources. One of the key areas of morbidity associated …

One of the leading causes of impaired wound healing is diabetes mellitus. Unlike other
causes of altered tissue repair, there are multiple factors that contribute to the impairment …

Background: Nonhealing ulcers affect patient quality of life and impose a substantial
financial burden on the health care system. Purpose: To systematically evaluate benefits …

The results of a combined analysis and separate analyses of four multicenter, randomized,
parallel group studies that evaluated the effects of once‐daily topical administration of …

Current treatment approaches toward spinal cord injuries (SCI) have mainly focused on
overcoming the inhibitory microenvironment that surrounds lesion sites. Unfortunately, the …

Debridement of diabetic foot ulcers - Edwards, J - 2010 | Cochrane Library Skip to Content
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Background Foot ulcers are a major complication of diabetes mellitus, often leading to
amputation. Growth factors derived from blood platelets, endothelium, or macrophages …

Background: Diabetic foot ulcer is a major health care problem that leads to amputation.
Methods: Patients with full-thickness diabetic neurotrophic foot ulcers present for longer than …