Radiolabelling of nanomaterials for medical imaging and therapy
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …
medical imaging and therapy. Over the last two decades, there has been an increasing effort …
Rheumatoid arthritis microenvironment insights into treatment effect of nanomaterials
Y Zhu, T Zhao, M Liu, S Wang, S Liu, Y Yang, Y Yang… - Nano Today, 2022 - Elsevier
Rheumatoid arthritis (RA) causes a huge medical burden due to its high morbidity and
disability rate. Emerging evidences demonstrate that RA has a tumor-like microenvironment …
disability rate. Emerging evidences demonstrate that RA has a tumor-like microenvironment …
Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium
The therapeutic potential of liposomes to deliver drugs into inflamed tissue is well
documented. Liposomes are believed to largely transport drugs into inflamed joints by …
documented. Liposomes are believed to largely transport drugs into inflamed joints by …
PET Imaging of Small Extracellular Vesicles via [89Zr]Zr(oxinate)4 Direct Radiolabeling
Exosomes or small extracellular vesicles (sEVs) are increasingly gaining attention for their
potential as drug delivery systems and biomarkers of disease. Therefore, it is important to …
potential as drug delivery systems and biomarkers of disease. Therefore, it is important to …
[HTML][HTML] Radiolabelling of extracellular vesicles for PET and SPECT imaging
AA Khan, RTM de Rosales - Nanotheranostics, 2021 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) such as exosomes and microvesicles have gained recent
attention as potential biomarkers of disease as well as nanomedicinal tools, but their …
attention as potential biomarkers of disease as well as nanomedicinal tools, but their …
Imaging inflammation with positron emission tomography
J Iking, M Staniszewska, L Kessler, JM Klose… - Biomedicines, 2021 - mdpi.com
The impact of inflammation on the outcome of many medical conditions such as
cardiovascular diseases, neurological disorders, infections, cancer, and autoimmune …
cardiovascular diseases, neurological disorders, infections, cancer, and autoimmune …
[HTML][HTML] A kit formulation for the preparation of [89Zr] Zr (oxinate) 4 for PET cell tracking: White blood cell labelling and comparison with [111In] In (oxinate) 3
Background Advances in immunology and cell-based therapies are creating a need to track
individual cell types, such as immune cells (neutrophils, eosinophils, chimeric antigen …
individual cell types, such as immune cells (neutrophils, eosinophils, chimeric antigen …
Translational considerations in nanomedicine: the oncology perspective
Nanoparticles can provide effective control of the release rate and tissue distribution of their
drug payload, leading to major pharmacokinetic and pharmacodynamic changes vis-à-vis …
drug payload, leading to major pharmacokinetic and pharmacodynamic changes vis-à-vis …
In vivo real-time positron emission particle tracking (PEPT) and single particle PET
Positron emission particle tracking (PEPT) enables 3D localization and tracking of single
positron-emitting radiolabelled particles with high spatiotemporal resolution. The translation …
positron-emitting radiolabelled particles with high spatiotemporal resolution. The translation …
Liposomal antagomiR‐155‐5p restores anti‐inflammatory macrophages and improves arthritis in preclinical models of rheumatoid arthritis
A Paoletti, B Ly, C Cailleau, F Gao… - Arthritis & …, 2024 - Wiley Online Library
Objective We previously reported an increased expression of microRNA‐155 (miR‐155) in
the blood monocytes of patients with rheumatoid arthritis (RA) that could be responsible for …
the blood monocytes of patients with rheumatoid arthritis (RA) that could be responsible for …