Sporulation in the Budding Yeast Saccharomyces cerevisiae

AM Neiman - Genetics, 2011 - academic.oup.com
In response to nitrogen starvation in the presence of a poor carbon source, diploid cells of
the yeast Saccharomyces cerevisiae undergo meiosis and package the haploid nuclei …

[HTML][HTML] Ready, SET, Go: Post-translational regulation of the histone lysine methylation network in budding yeast

RJ Separovich, MR Wilkins - Journal of Biological Chemistry, 2021 - ASBMB
Histone lysine methylation is a key epigenetic modification that regulates eukaryotic
transcription. Here, we comprehensively review the function and regulation of the histone …

[HTML][HTML] Rph1/KDM4 mediates nutrient-limitation signaling that leads to the transcriptional induction of autophagy

A Bernard, M Jin, P González-Rodríguez, J Füllgrabe… - Current biology, 2015 - cell.com
Background Autophagy is a conserved process mediating vacuolar degradation and
recycling. Autophagy is highly upregulated upon various stresses and is essential for cell …

[HTML][HTML] Serine-and threonine/valine-dependent activation of PDK and Tor orthologs converge on Sch9 to promote aging

MG Mirisola, G Taormina, P Fabrizio, M Wei, J Hu… - PLoS …, 2014 - journals.plos.org
Dietary restriction extends longevity in organisms ranging from bacteria to mice and protects
primates from a variety of diseases, but the contribution of each dietary component to aging …

[HTML][HTML] Gis1 and Rph1 regulate glycerol and acetate metabolism in glucose depleted yeast cells

J Orzechowski Westholm, S Tronnersjö, N Nordberg… - PloS one, 2012 - journals.plos.org
Aging in organisms as diverse as yeast, nematodes, and mammals is delayed by caloric
restriction, an effect mediated by the nutrient sensing TOR, RAS/cAMP, and AKT/Sch9 …

[HTML][HTML] Mechanism of enhanced salt tolerance in Saccharomyces cerevisiae by CRZ1 overexpression

F Zuo, Y Wu, Y Sun, C Xie, Y Tang - Scientific Reports, 2024 - nature.com
Achieving high-gravity fermentation in the industrial production of fuel ethanol, and
enhancing the fermentation efficiency of high-salt raw materials, such as waste molasses …

A visual screen of protein localization during sporulation identifies new components of prospore membrane-associated complexes in budding yeast

C Lam, E Santore, E Lavoie, L Needleman… - Eukaryotic …, 2014 - Am Soc Microbiol
During ascospore formation in Saccharomyces cerevisiae, the secretory pathway is
reorganized to create new intracellular compartments, termed prospore membranes …

JmjN interacts with JmjC to ensure selective proteolysis of Gis1 by the proteasome

Z Quan, SG Oliver, N Zhang - Microbiology, 2011 - microbiologyresearch.org
A group of JmjC domain-containing proteins also harbour JmjN domains. Although the JmjC
domain is known to possess histone demethylase activity, the function of the JmjN domain …

Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family

S Lal, JM Comer, PC Konduri, A Shah… - Nucleic Acids …, 2018 - academic.oup.com
The yeast Gis1 protein is a transcriptional regulator belonging to the JMJD2/KDM4 subfamily
of demethylases that contain a JmjC domain, which are highly conserved from yeast to …

[HTML][HTML] Heme, a metabolic sensor, directly regulates the activity of the KDM4 histone demethylase family and their interactions with partner proteins

PC Konduri, T Wang, N Salamat, L Zhang - Cells, 2020 - mdpi.com
The KDM4 histone demethylase subfamily is constituted of yeast JmjC domain-containing
proteins, such as Gis1, and human Gis1 orthologues, such as KDM4A/B/C. KDM4 proteins …