[HTML][HTML] Detection of carbapenemases in Enterobacteriaceae: a challenge for diagnostic microbiological laboratories

J Hrabák, E Chudáčková, CC Papagiannitsis - Clinical Microbiology and …, 2014 - Elsevier
Carbapenemase-producing bacteria have now spread all over the world. Infections caused
by those bacteria are difficult to treat. Therefore, there is an urgent need for accurate and fast …

Matrix-assisted laser desorption ionization–time of flight mass spectrometry for the rapid detection of antimicrobial resistance mechanisms and beyond

M Oviaño, G Bou - Clinical Microbiology Reviews, 2018 - Am Soc Microbiol
Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF
MS) has been successfully applied in recent years for first-line identification of pathogens in …

Progress on the development of rapid methods for antimicrobial susceptibility testing

MR Pulido, M García-Quintanilla… - Journal of …, 2013 - academic.oup.com
Antimicrobial susceptibility testing is essential for guiding the treatment of many types of
bacterial infections, especially in the current context of rising rates of antibiotic resistance …

Efficient detection of carbapenemase activity in Enterobacteriaceae by matrix-assisted laser desorption ionization− time of flight mass spectrometry in less than 30 …

C Lasserre, L De Saint Martin, G Cuzon… - Journal of clinical …, 2015 - Am Soc Microbiol
The recognition of carbapenemase-producing Enterobacteriaceae (CPE) isolates is a major
laboratory challenge, and their inappropriate or delayed detection may have negative …

[HTML][HTML] Insights on the Horizontal Gene Transfer of Carbapenemase Determinants in the Opportunistic Pathogen Acinetobacter baumannii

GJ Da Silva, S Domingues - Microorganisms, 2016 - mdpi.com
Horizontal gene transfer (HGT) is a driving force to the evolution of bacteria. The fast
emergence of antimicrobial resistance reflects the ability of genetic adaptation of pathogens …

[HTML][HTML] A high mortality rate associated with multidrug-resistant Acinetobacter baumannii ST79 and ST25 carrying OXA-23 in a Brazilian intensive care unit

KE da Silva, WG Maciel, J Croda, R Cayô, AC Ramos… - PLoS …, 2018 - journals.plos.org
The global spread of carbapenem-resistant Acinetobacter baumannii (A. baumannii) strains
has restricted the therapeutic options available to treat infections due to this pathogen …

Current methods for the identification of carbapenemases

AZ Bialvaei, HS Kafil, M Asgharzadeh… - Journal of …, 2016 - Taylor & Francis
Detection of carbapenemases in clinical microbiology labs is a challenging issue.
Comparison of the results of susceptibility testing with the breakpoint values of carbapenems …

Detection of carbapenemase activity directly from blood culture vials using MALDI-TOF MS: a quick answer for the right decision

CG Carvalhaes, R Cayô, MF Visconde… - Journal of …, 2014 - academic.oup.com
Objectives Recently, matrix-assisted laser desorption ionization–time-of-flight mass
spectrometry (MALDI-TOF MS) was successfully applied for the detection of carbapenemase …

[HTML][HTML] One system for all: is mass spectrometry a future alternative for conventional antibiotic susceptibility testing?

M Welker, A Van Belkum - Frontiers in microbiology, 2019 - frontiersin.org
The two main pillars of clinical microbiological diagnostics are the identification of potentially
pathogenic microorganisms from patient samples and the testing for antibiotic susceptibility …

[HTML][HTML] Synergistic effects of Cinnamomum cassia L. essential oil in combination with polymyxin B against carbapenemase-producing Klebsiella pneumoniae and …

NG Vasconcelos, JHFS Queiroz, KE Silva… - PLoS …, 2020 - journals.plos.org
Multidrug resistance prompts the search for new sources of antibiotics with new targets at
bacteria cell. To investigate the antibacterial activity of Cinnamomum cassia L. essential oil …