Luteolin ameliorates inflammation and Th1/Th2 imbalance via regulating the TLR4/NF-κB pathway in allergic rhinitis rats

J Dong, O Xu, J Wang, C Shan… - Immunopharmacology and …, 2021 - Taylor & Francis
Objective Luteolin has an anti-allergic effect but its mechanism is not clear. This study
attempted to determine the mechanisms of luteolin in rhinitis. Methods Allergic rhinitis rat …

New drugs in early-stage clinical trials for allergic rhinitis

E Heffler, L Brussino, S Del Giacco… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Allergic rhinitis (AR) is the most common allergic disease, and it has a relevant
impact on the quality of life of the patient. Treatment of AR includes a combination of …

Global trend and risk factors of the disease burden for pharynx and larynx cancers between 1990 and 2019: a systematic analysis of the global burden of disease …

A Huang, X Wu, J Song, YT Wang, Y Yao, Z Liu… - BMC Public Health, 2022 - Springer
Background Pharynx and larynx cancers (PLCs) are the top killer cancers in head and neck
and significantly affect the quality of life of patients. A detailed study examining the disease …

The amendatory effect of hesperidin and thymol in allergic rhinitis: an ovalbumin-induced rat model

K Kilic, MS Sakat, S Yildirim, FM Kandemir… - European Archives of …, 2019 - Springer
Purpose Allergic rhinitis is an immunoglobulin-E (Ig-E)-mediated response driven by type 2
helper T cells. Hesperidin and thymol are biological agents that possess antioxidant and anti …

A novel nasal co-loaded loratadine and sulpiride nanoemulsion with improved downregulation of TNF-α, TGF-β and IL-1 in rabbit models of ovalbumin-induced …

SA Mohamad, MA Safwat, M Elrehany, SA Maher… - Drug …, 2021 - Taylor & Francis
Purpose The work aimed to develop a co-loaded loratadine and sulpiride nasal
nanoemulsion for allergic rhinitis management. Methods Compatibility studies were …

Astragalus polysaccharides/chitosan microspheres for nasal delivery: preparation, optimization, characterization, and pharmacodynamics

S Wang, Y Sun, J Zhang, X Cui, Z Xu, D Ding… - Frontiers in …, 2020 - frontiersin.org
Chitosan (CTS) constitutes a promising area in treatment of nose-related diseases as a
nasal drug delivery carrier. Astragalus polysaccharide (APS) significantly attenuates …

The ameliorative effect of berberine and coenzyme Q10 in an ovalbumin-induced allergic rhinitis model

MS Sakat, K Kilic, FM Kandemir, S Yildirim… - European Archives of …, 2018 - Springer
Purpose Berberine and coenzyme Q10 (CoQ10) are agents with anti-inflammatory and
antioxidant characteristics. The purpose of this study was to investigate the effectiveness of …

Effects of a thermosensitive in situ gel containing mometasone furoate on a rat allergic rhinitis model

E Altuntaş, G Yener, R Doğan, F Aksoy… - American Journal of …, 2018 - journals.sagepub.com
Background Mometasone furoate, one of the second generation intranasal corticosteroids, is
currently used in suspension form due to its poor solubility. However, this is not favorable for …

Mechanistic study of acupuncture on the pterygopalatine ganglion to improve allergic rhinitis: analysis of multi-target effects based on bioinformatics/network topology …

M Tian, W Sun, Y Mao, Y Zhang, H Liu… - Briefings in …, 2024 - academic.oup.com
One of the prevalent chronic inflammatory disorders of the nasal mucosa, allergic rhinitis
(AR) has become more widespread in recent years. Acupuncture pterygopalatine ganglion …

The Role of Substance P Receptor Antagonists in Allergic Rhinitis: Ovalbumin‐Induced Rat Model

Ç Becerik, ÇT Karaca, Z Özcan, S Kul… - The …, 2023 - Wiley Online Library
Objective Substance P is a peptide from the tachykinin family, which is found in peripheral
and central nervous systems, causing vasodilation and increased secretion in the nasal …