Bacterial chemoreceptors: high-performance signaling in networked arrays

GL Hazelbauer, JJ Falke, JS Parkinson - Trends in biochemical sciences, 2008 - cell.com
Chemoreceptors are crucial components in the bacterial sensory systems that mediate
chemotaxis. Chemotactic responses exhibit exquisite sensitivity, extensive dynamic range …

Transmembrane signaling in bacterial chemoreceptors

JJ Falke, GL Hazelbauer - Trends in biochemical sciences, 2001 - cell.com
Bacterial chemoreceptors mediate chemotaxis by recognizing specific chemicals and
regulating a noncovalently associated histidine kinase. Ligand binding to the external …

Signal transduction in bacterial chemotaxis

MD Baker, PM Wolanin, JB Stock - Bioessays, 2006 - Wiley Online Library
Motile bacteria respond to environmental cues to move to more favorable locations. The
components of the chemotaxis signal transduction systems that mediate these responses …

How signals are heard during bacterial chemotaxis: protein-protein interactions in sensory signal propagation

A Bren, M Eisenbach - Journal of bacteriology, 2000 - Am Soc Microbiol
Chemotaxis is a mechanism by which bacteria efficiently and rapidly respond to changes in
the chemical composition of their environment, approaching chemically favorable …

Cellular stoichiometry of the components of the chemotaxis signaling complex

M Li, GL Hazelbauer - Journal of bacteriology, 2004 - Am Soc Microbiol
The chemotactic sensory system of Escherichia coli comprises membrane-embedded
chemoreceptors and six soluble chemotaxis (Che) proteins. These components form …

Nanodiscs separate chemoreceptor oligomeric states and reveal their signaling properties

T Boldog, S Grimme, M Li, SG Sligar… - Proceedings of the …, 2006 - National Acad Sciences
Bacterial chemoreceptors are transmembrane homodimers that can form trimers, higher
order arrays, and extended clusters as part of signaling complexes. Interactions of dimers in …

Spatial organization in bacterial chemotaxis

V Sourjik, JP Armitage - The EMBO journal, 2010 - embopress.org
Spatial organization of signalling is not an exclusive property of eukaryotic cells. Despite the
fact that bacterial signalling pathways are generally simpler than those in eukaryotes, there …

Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis

TS Shimizu, N Le Novère, MD Levin, AJ Beavil… - Nature cell …, 2000 - nature.com
Coliform bacteria detect chemical attractants by means of a membrane-associated cluster of
receptors and signalling molecules. We have used recently determined molecular …

Precise adaptation in bacterial chemotaxis through “assistance neighborhoods”

RG Endres, NS Wingreen - Proceedings of the National …, 2006 - National Acad Sciences
The chemotaxis network in Escherichia coli is remarkable for its sensitivity to small relative
changes in the concentrations of multiple chemical signals over a broad range of ambient …

Collaborative signaling by bacterial chemoreceptors

JS Parkinson, P Ames, CA Studdert - Current opinion in microbiology, 2005 - Elsevier
Motile bacteria seek optimal living habitats by following gradients of attractant and repellent
chemicals in their environment. The signaling machinery for these chemotactic behaviors …