Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications

Q Tuo, S Zhang, P Lei - Medicinal research reviews, 2022 - Wiley Online Library
Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

Programming inflammatory cell death for therapy

S Christgen, RE Tweedell, TD Kanneganti - Pharmacology & therapeutics, 2022 - Elsevier
Programmed cell death (PCD) is an essential part of organismal development and plays
fundamental roles in host defense against pathogens and the maintenance of homeostasis …

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

L Galluzzi, I Vitale, SA Aaronson, JM Abrams… - Cell Death & …, 2018 - nature.com
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

Neuronal cell death

M Fricker, AM Tolkovsky, V Borutaite… - Physiological …, 2018 - journals.physiology.org
Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …

Cell death mechanisms in eukaryotes

JG Nirmala, M Lopus - Cell biology and toxicology, 2020 - Springer
Like the organism they constitute, the cells also die in different ways. The death can be
predetermined, programmed, and cleanly executed, as in the case of apoptosis, or it can be …

[HTML][HTML] Ischemia/reperfusion

T Kalogeris, CP Baines, M Krenz… - Comprehensive …, 2016 - ncbi.nlm.nih.gov
Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

Molecular mechanisms of parthanatos and its role in diverse diseases

P Huang, G Chen, W Jin, K Mao, H Wan… - International journal of …, 2022 - mdpi.com
Differential evolution of apoptosis, programmed necrosis, and autophagy, parthanatos is a
form of cell death mediated by poly (ADP-ribose) polymerase 1 (PARP1), which is caused by …

Live to die another way: modes of programmed cell death and the signals emanating from dying cells

Y Fuchs, H Steller - Nature reviews Molecular cell biology, 2015 - nature.com
All life ends in death, but perhaps one of life's grander ironies is that it also depends on
death. Cell-intrinsic suicide pathways, termed programmed cell death (PCD), are crucial for …

Consensus guidelines for the detection of immunogenic cell death

O Kepp, L Senovilla, I Vitale, E Vacchelli… - …, 2014 - Taylor & Francis
Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit
immune responses specific for dead cell-associated antigens. However, multiple stimuli can …

Autophagy and apoptosis cascade: which is more prominent in neuronal death?

R Gupta, RK Ambasta, P Kumar - Cellular and molecular life sciences, 2021 - Springer
Autophagy and apoptosis are two crucial self-destructive processes that maintain cellular
homeostasis, which are characterized by their morphology and regulated through signal …