Unveiling the future of metabolic medicine: omics technologies driving personalized solutions for precision treatment of metabolic disorders
Metabolic disorders are increasingly prevalent worldwide, leading to high rates of morbidity
and mortality. The variety of metabolic illnesses can be addressed through personalized …
and mortality. The variety of metabolic illnesses can be addressed through personalized …
Multi-omics profiling: the way toward precision medicine in metabolic diseases
C Hu, W Jia - Journal of molecular cell biology, 2021 - academic.oup.com
Metabolic diseases including type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver
disease (NAFLD), and metabolic syndrome (MetS) are alarming health burdens around the …
disease (NAFLD), and metabolic syndrome (MetS) are alarming health burdens around the …
[HTML][HTML] Diabetes mellitus and periodontitis share intracellular disorders as the main meeting point
Diabetes and periodontitis are two of the most prevalent diseases worldwide that negatively
impact the quality of life of the individual suffering from them. They are part of the chronic …
impact the quality of life of the individual suffering from them. They are part of the chronic …
Multiomics technologies: role in disease biomarker discoveries and therapeutics
Medical research has been revolutionized after the publication of the full human genome.
This was the major landmark that paved the way for understanding the biological functions …
This was the major landmark that paved the way for understanding the biological functions …
[HTML][HTML] Overview of transcriptomic research on type 2 diabetes: challenges and perspectives
ZN Tonyan, YA Nasykhova, MM Danilova, YA Barbitoff… - Genes, 2022 - mdpi.com
Type 2 diabetes (T2D) is a common chronic disease whose etiology is known to have a
strong genetic component. Standard genetic approaches, although allowing for the …
strong genetic component. Standard genetic approaches, although allowing for the …
[HTML][HTML] The function of KDEL receptors as UPR genes in disease
ES Wires, KA Trychta, LM Kennedy… - International journal of …, 2021 - mdpi.com
The KDEL receptor retrieval pathway is essential for maintaining resident proteins in the
endoplasmic reticulum (ER) lumen. ER resident proteins serve a variety of functions …
endoplasmic reticulum (ER) lumen. ER resident proteins serve a variety of functions …
The prospect of genomic, transcriptomic, epigenetic and metabolomic biomarkers for the personalized prevention of type 2 diabetes and cardiovascular diseases
A Zeljkovic, M Mihajlovic, S Vujcic… - Current Vascular …, 2023 - ingentaconnect.com
Cardiometabolic diseases, such as type 2 diabetes mellitus (DM) and cardiovascular
disease (CVD), are a great health concern. The strategies aimed to increase awareness and …
disease (CVD), are a great health concern. The strategies aimed to increase awareness and …
[HTML][HTML] Whole transcriptome RNA-seq reveals key regulatory factors involved in type 2 diabetes pathology in peripheral fat of Asian Indians
A Saxena, N Mathur, P Tiwari, SK Mathur - Scientific reports, 2021 - nature.com
Abstract The prevalence of Type 2 Diabetes has reached an epidemic proportion particularly
in south Asian countries. We have earlier shown that the anatomical fat distribution, termed …
in south Asian countries. We have earlier shown that the anatomical fat distribution, termed …
[HTML][HTML] Recent progress in the diagnosis and management of type 2 diabetes mellitus in the era of COVID-19 and single cell multi-omics technologies
K Kupai, T Várkonyi, S Török, V Gáti, Z Czimmerer… - Life, 2022 - mdpi.com
Type 2 diabetes mellitus (T2DM) is one of the world's leading causes of death and life-
threatening conditions. Therefore, we review the complex vicious circle of causes …
threatening conditions. Therefore, we review the complex vicious circle of causes …
Diet‐induced prediabetes: Effects on the activity of the renin–angiotensin–aldosterone system in selected organs
BC Mkhize, P Mosili, PS Ngubane… - Journal of Diabetes …, 2022 - Wiley Online Library
Abstract Aims/Introduction Derangements often observed with type 2 diabetes are
associated with disturbances in renin–angiotensin–aldosterone system (RAAS) activity. A …
associated with disturbances in renin–angiotensin–aldosterone system (RAAS) activity. A …