[HTML][HTML] Alzheimer's disease pathophysiology in the retina
The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …
Near-infrared fluorescent probes as imaging and theranostic modalities for amyloid-beta and tau aggregates in Alzheimer's disease
A person suspected of having Alzheimer's disease (AD) is clinically diagnosed for the
presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in …
presence of principal biomarkers, especially misfolded amyloid-beta (Aβ) and tau proteins in …
Curcumin-loaded mesoporous silica nanoparticles for drug delivery: synthesis, biological assays and therapeutic potential–a review
Curcumin-loaded mesoporous silica nanoparticles (MSNs) have shown promise as drug
delivery systems to address the limited pharmacokinetic characteristics of curcumin …
delivery systems to address the limited pharmacokinetic characteristics of curcumin …
Past, present and future role of retinal imaging in neurodegenerative disease
AH Kashani, S Asanad, JW Chan, MB Singer… - Progress in retinal and …, 2021 - Elsevier
Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …
of information about the structure, function and molecular composition of retinal tissue in …
Alzheimer's retinopathy: seeing disease in the eyes
The neurosensory retina emerges as a prominent site of Alzheimer's disease (AD)
pathology. As a CNS extension of the brain, the neuro retina is easily accessible for …
pathology. As a CNS extension of the brain, the neuro retina is easily accessible for …
Retinal vasculopathy in Alzheimer's disease
The retina has been increasingly investigated as a site of Alzheimer's disease (AD)
manifestation for over a decade. Early reports documented degeneration of retinal ganglion …
manifestation for over a decade. Early reports documented degeneration of retinal ganglion …
Application of curcumin nanoformulations in Alzheimer's disease: prevention, diagnosis and treatment
H Lv, Y Wang, X Yang, G Ling, P Zhang - Nutritional neuroscience, 2023 - Taylor & Francis
Objectives: Alzheimer's disease (AD) is a serious neurodegenerative disease. Although
many therapeutic strategies have been studied, their clinical applications are immature …
many therapeutic strategies have been studied, their clinical applications are immature …
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative …
Single cell RNA sequencing studies identified novel neurodegeneration-associated
microglial (MGnD/DAM) subtypes activated around cerebral amyloid plaques. Micro-RNA …
microglial (MGnD/DAM) subtypes activated around cerebral amyloid plaques. Micro-RNA …
Action mechanisms of curcumin in Alzheimer's disease and its brain targeted delivery
D Ege - Materials, 2021 - mdpi.com
AD is a chronic neurodegenerative disease. Many different signaling pathways, such as
Wnt/β-catenin, Notch, ROS/JNK, and PI3K/Akt/mTOR are involved in Alzheimer's disease …
Wnt/β-catenin, Notch, ROS/JNK, and PI3K/Akt/mTOR are involved in Alzheimer's disease …
Amyloid beta immunoreactivity in the retinal ganglion cell layer of the Alzheimer's eye
S Lee, K Jiang, B McIlmoyle, E To, Q Xu… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is the most prevalent form of dementia, accounting for 60–70% of
all dementias. AD is often under-diagnosed and recognized only at a later, more advanced …
all dementias. AD is often under-diagnosed and recognized only at a later, more advanced …